胃液Prostaglandin Eの研究 第2編 消化性潰瘍および急性ビラン性胃炎における検討
スポンサーリンク
概要
- 論文の詳細を見る
Prostaglandin E (PGE) in the gastric juice of patients with peptic ulcer and acute erosive gastritis was determined by a radioimmunoassay. In gastric and duodenal ulcer patients, the concentration and output of PGE in the gastric juice were not significantly different from those of normal subjects both basally and after pentagastrin stimulation, but in acute erosive gastritis patients they showed significantly lower levels. The concentration of PGE in the gastric juice was lower in all cases after pentagastrin stimulation compared to the basal level because of dilution due to an increased gastric juice volume. After pentagastrin stimulation, PGE output tended to increase in all groups, but this increase was not statistically significant and probably was caused by an increased gastric juice volume. No correlation could be found among acid output, pepsin output and gastric PGE output. These results do not support the concept that endogenous PGE deficiency may be an etiological factor in peptic ulcer disease, and seem to argue against a possible inhibitory role of PGE in gastric acid secretion by a negative feedback mechanism in man. However, a low level of endogenous PGE may be intimately related to the pathogenesis of acute erosive gastritis.
- 岡山医学会の論文
- 1987-02-28
岡山医学会 | 論文
- エピジェネティクス
- 非小細胞肺癌における癌・精巣抗原XAGE-1の発現と免疫応答の解析
- 岡山大学耳鼻咽喉科における鼻アレルギーの臨床統計
- 難聴幼児訓練施設における幼児難聴の原因
- 乳管洗浄細胞診が診断に有効であった乳癌の一例