肝疾患におけるエンドトキシン抗体の臨床的意義について ―免疫グロブリン・クラスの成績も含めて―
スポンサーリンク
概要
- 論文の詳細を見る
The antibody, and its immunoglobulin class, against endotoxin (LPS ; E. coli 026 : B6) in sera from patients with various liver diseases was examined by the use of an enzyme-linked immunosorbent assay (ELISA). The IgG-antibody titer to endotoxin was high in sera from patients with liver cirrhosis (LC), fulminant hepatitis (FH), severe chronic active hepatitis (CAH2B), alcoholic hepatitis and acute hepatitis (AH), and its titer was associated with the severity of liver injury. The IgA-antibody titer was high in sera of patients with alcoholic hepatitis, FH, LC, CAH2B and AH. The patient with the highest titer had alcoholic hepatitis. The IgM-antibody titer was not associated with the severity of liver injury, but it was associated with the acute stage of acute hepatitis and acute exacerbation of chronic hepatitis. The antibody titer was higher in sera of LC patients with ascites and/or esophageal varices than in LC patients without them (especially IgA-antibody : p>0.01). The ELISA for detection of antibody to endotoxin was useful for clinical observation of patients with liver diseases.
- 1987-02-28
論文 | ランダム
- Glutathione Reductase Deficiency of Red Cells in Aplastic Anemia-1-Red Cell Enzyme Activities,Glycolytic Intermediates,Adenine Nucleotides and GSH Levels in 11 Cases with Aplastic Anemia
- Glutathione Reductase Deficiency of Red Cells in Aplastic Anemia-2-Effects of Flavine Compounds on Red Cell Glutathione Reductase
- 筑波大学附属学校における教育実習の予備調査及び教育実習充実のための方策
- 「妹背山婦女庭訓」試論 : 山の段の解釈
- 連歌新式注解書の研究