側坐核と辺縁系発作―燃え上がり現象を用いた研究
スポンサーリンク
概要
- 論文の詳細を見る
An antagonistic relationship between epilepsy and psychosis has been claimed. On the other hand, abnormality of the N. accumbens is thought to be involved in schizophrenia and temporal lobe epilepsy. In order to examine the role of the N. accumbens in limbic seizure and psychosis, the following were studied: 1. Amygdaloid kindling and the functional change of the N. accumbens, 2. Accumbens kindling, 3. Functional change of limbic nuclei following the accumbens kindling, and 4. The effects of lesioning of the N. accumbens on the amygdaloid kindling. The results were as follows: 1. The amygdaloid kindling induced epileptic focus and positive transfer into the N. accumbens. 2. The kindling phenomenon was confirmed positive by repeated stimulation of the N. accumbens. Clinicoelectrographic seizure development during the N. accumbens kindling resembled that of amygdaloid kindling. The mean minimum intensities to induce afterdischarge and kindling rate were 620μA and 23days, respectively. 3. Positive transfer was found in the N. amygdala and hippocampus following the accumbens kindling. 4. Lesioning of the N. accumbens had no effect on amygdaloid seizure development, but lowered the threshold intensity to induce amygdaloid afterdischarge after kindling. It was concluded that the N. accumbens and the N. amygdala formed epileptic hyperexcitability reciprocally and that the N. accumbens had an inhibitory effect on the limbic seizure, but no effect on the developed amygdaloid kindling.
- 1982-02-28
論文 | ランダム
- 1-2 運動前の運動強度に関する情報は運動時の生理的反応を変える(日本生理人類学会第62回大会発表要旨,学会記事)
- 経腸栄養時の液体栄養剤症候群--より生理的な胃瘻からの経腸栄養法をめざして (特集 イラストと画像でわかる! 消化器疾患の栄養療法(1)消化管編)
- 政局 民主敗北「愛想尽かされた」--菅直人はお遍路に出ろ/[2010]年内に追い込まれ解散 (参院選特集)
- プレゼンテーション能力の評価方法確立のための書籍調査とその評価法を用いた情報システムの開発
- 菅首相が所信表明、「強い社会保障」を強調--社会保障の充実は雇用や経済成長もたらす