Clinical applications of neurotransmitter-receptor studies in geriatric neuropharmacology.
スポンサーリンク
概要
- 論文の詳細を見る
<p>The use of ligand-binding methods to study neurotransmitter-receptor sites has made its impact on almost all aspects of biological pursuits including research on aging and neurodegenerative diseases. In the past, most of the research in biochemical gerontology has largely centered around changes in various neurotransmitters and enzymatic activities. The molecular basis of aging and neurodegeneration at the level of neurotransmitter-receptor interactions has been highly appreciated in the last two decades as a result of receptor binding studies. It is now possible to obtain information about the regional distribution of neurotransmitter receptors in the brain, the pharmacological and biochemical characteristics of these sites, and the functional interrelationships between different neuronal systems in normal and pathological conditions. The passage of time after maturity is accompanied by measurable physiologic decline in virtually all systems. It is the aim of this work to discuss the practical aspects of neurotransmitter and/or drug (ligand)-receptor binding studies, highlighting some examples of their applications to geriatric neuropharmacology research, with special consideration to learning impairment and memory loss in normal and in pathological aging processes.</p>
論文 | ランダム
- キサントゲン酸エステルと第三アミンとの反応
- メチルキサントゲン酸エステルとトリエチルアミンとの反応
- 最近のウロストミーケア : 第85回広島地方会
- 腎盂尿管腫揚の臨床的観察 : 第85回広島地方会
- 腎被膜下血腫の5例 : 第44回四国地方会