副腎皮質に結節性過形成,腺腫が共存し,術後,高カリウム血症をきたした原発性アルドステロン症の1例

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A 55-year-old woman with primary aldosteronism who had been treated with spironolactone underwent an operation which consisted of removal of a unilateral adrenal tumor and subtotal resection of the remaining adrenal gland. The surgery resulted in hyperkalemia without lowering her high blood pressure. Histological examination of removed specimens showed adrenocortical adenoma and micro nodular hyperplasia. This case concerns a hyperkalemic change following the operation. The functional significance of micronodular hyperplasia is also discussed.