膀胱腫瘍の臨床的観察

概要

論文の詳細を見る
The subjects of these studies were 240 patients with primary bladder tumors, who were treated in the Urological Department of Mie University Hospital and of Shiohama Hospital during 10 years from Jan. 1965 to Dec. 1974. Of these cases, the incidence rate, cystoscopic findings, histologic findings, therapy of follow-up studies are reported as follows. 1) Incidence : Two hundred and forty patients with bladder tumors were 1.10 per cent of the total number of out-patients treated at the above hospitals, the ratio between male and female patients was 4:1. About ninety-five per cent of patients with bladder tumors were over forty years of age. The highest percentage of affected patients (32.9%) was in their sixties followed by those in their seventies, fifties, and forties. 2) Cystoscopic findings : The sites of the neoplastic growths mostly originated on the lateral wall of the bladder and less so on the trigone and the posterior wall and there were even fewer cases on the bladder neck, the dome area of the anterior wall. Most of tumors (61.3%) showed single growths compared with multiple growths (38.796). The tumors were from rice grain to walnut in size and had various shapes. Of all the cases studied there were 93 papillary and pedunculated cases (54.7%), 39 papillary and sessile cases (22.4%) and 38 non-papillary and sessile cases. 3) Histologic findings : Of 1S9 cases histologically examined, lSI cases (95.1%) were transitional cell carcinoma, the the grading of which was as follows: 17 cases Grade I (11.3%), 74 cases Grade II (49.0%), 47 cases Grade III (31.1%) and 13 cases Grade IV (8.6%), respectively. The number of patients with squamous cell carcinoma was 4 (2.5%) and with adenocarcinoma 3 (1.9%), including 2 with urachal adenocarcinoma. Concerning non-epithelial tumors, a case of leiomyosarcoma (0.696) was noted. There was no evidence of any relationship between the grading of the tumors and the chief complaints of the patients. Most of the small or tiny growths were histologically characterized by well differentiated transitonal cell carcinoma (Grade I or II), while medium or large sized tumors showed low differentiation in appearance (Grade III or IV). The papillary and sessile tumors were largely characterized by well-differentiated transitional cell carcinoma, compared with the non-papillary tumors showing mostly lower differentiation in histological types. There was no apparent relationship between the grading of the tumors and the ages of the patients. 4) Five-year survival : Of the 56 patients periodically checked, the survival rate of 5 years was 71.6 per cent. Among the patients with TUEC or TUR treatment, the 5-year survival was 84.6 per cent, while the 5-year survival among patients with partial cystectomy was 75.8 per cent. The 5-year survival among patients with surgical therapy in association with chemotherapy and among patients with surgery and radiotherapy was similar (75.0% and 71.4%, respectively), though with the recurrence of tumors, radiotherapy associated with surgery proved more effective than chemotherapy alone.

著者

浜野耕一郎
開院

膀胱腫瘍の臨床的観察

スポンサーリンク

概要

著者

関連論文

スポンサーリンク