Klinefelter症候群にかんする臨床的研究 2.Xg式血液型検査によるX染色体不分離現象の解析

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• The origin of an additional X chromosome in XXY Klinefelter's syndrome was investigated by Xg blood group as a marker. Five patients and their parents received the test for this blood group. One out of five families showed father Xg (a+), mother Xg (a-) and son Xg (a+), suggesting X chromosome non-disjuction at the first meiosis in spermatogenesis, The sex chromosome of this patient could be described as XPXMY, and the reports of such are still few. It is interesting that the patients with this type of chromosome anomaly usually have young fathers at their birth.

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