[症例報告]脳血管障害により記憶障害をきたした2症例の事象関連電位: (ERP) Dynamic Topography

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A new method of Dynamic Topography of auditory event-related potentials (ERP) was reported with clinical application. ERPs were recorded during presentation of auditory stimuli. The stimuli consisted of 1 KHz tone-burst (inattentive) and 2 KHz tone-burst(attentive). The probabilities of frequent stimuli and rare stimuli were 0.8 and 0.2, respectively. The subjects were instructed to count the number of the rare tones. The scalp EEG from 16 scalp electrodes referenced to linked ears and positioned according to the international 10-20 system was recorded. ERPs to attentive stimuli were topographically demonstrated using 「Topography No.200 SPJ」 These two-dimensional maps were recorded as a series of pictures by video tapes. We call this method Dynamic ERP Topography. Case 1 was 67-years-old male with memory disturbance caused by left frontal lobe infarction. Case 2 was 57-years-old female wiht multi-infarct dementia. In both two patients with impaired memory, the patterns of Dynamic ERP Topography showed different ones from healthy subjects. In conclusion, Dynamic ERP Topography would be a useful method to investigate the disturbance of information-processing system in psychiatric disorders.
琉球大学医学部,Faculty of Medicine, University of the Ryukyusの論文