小腸平滑筋のリン脂質代謝に関する研究 ラット小腸平滑筋におけるリン脂質の in vitro での合成, 分解について
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Phospholipid metabolism in the small intestinal smooth muscle was investigated in vitro. The small intestines were incubated in a Krebs-Ringer bicarbonate solution (pH 7.4) at 37℃ containing 32Pi at various time intervals. The results clearly showed that the small intestinal smooth muscle synthesized phospholipids in situ, in spite of the fact that the degree of 32Pi incorporation into the phospholipids was lower than that of the liver and small intestinal mucosa. Among the phospholipids, specific radioactivity (SA) of phosphatidylinositol (PLI) separated from phosphatidylserine (PLS) was already higher than that of phosphatidic acid (PA) at 30 min incubation and also clearly higher than those of other phospholipids at 60 and 120 min. The same tendency was observed in the mucosa. SA of PLS was very low at each incubation time. SA of phosphatidylcholine (PLC) was already higher than that of phosphatidylethanolamine (PLE) at 30 min. The difference was more significant in incubation at a longer length of time. This is quite opposite to that observed in the liver, that is to say, under the same conditions SA of PLE was always higher than that of PLC in the latter. In the incubation conditions used, degradation of the phospholipids was recognized in the smooth muscle as well as in the mucosa. The degree of the individual phospholipids was not always similar when the incubation time was short. In the percentage of decrease of the phospholipids it was found that the values were in the following order : PLI>PLE>PLC. However, the difference in degree of decrease among the individual phospholipids could not be observed in incubation at a longer length of time. In PLE fraction, which consisted of three types, namely, diacyl, alkyl-acyl and alkenyl-acyl, hydrolysis of the diacyl fraction was more significant than those of the other two fractions.
- 1975-08-30
論文 | ランダム
- 「僕の物語」における「の」の物語
- 零號琴(第17回)
- 次世代作家ガイド (特集 伊藤計劃以後)
- 「ゲーム」からみた「伊藤計劃以後」 (特集 伊藤計劃以後) -- (小説外の想像力)
- コミック 野蛮なSF--『進撃の巨人』が「進」むのは、どちらか (特集 伊藤計劃以後) -- (小説外の想像力)