ラット舌のリン脂質組成およびphosphatidylcholineとphosphatidylethanolamineの脂肪酸組成について
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Detailed analyses of phospholipid were performed with rat tongue. The results were compared with those of rat skeletal muscles of the calves of hind legs. 1. The contents of lipid-phosphorus and protein per gram of tissue (wet weight) were 555/μg and 179 mg, respectively. The value of a ratio of phospholipid to protein was 3.1, which was lower than that in the liver and higher than that in the skeletal muscle. 2. The percent distribution of phosphatidylcholine in the tongue was lower than that in the skeletal muscle, while the relation in phosphatidylethanolamine between the two tissues was opposite. The percent of cardiolipin was slightly higher in the tongue than in the skeletal muscle. There were no remarkable differences among other phospholipids. 3. The occurrence of alkenyl-acyl and alkyl-acyl glycerylphosphorylcholine and -ethanolamine was shown and the composition of these two types and a diacyl type of each phospholipid was determined. The PLC fraction consisted mostly of the diacyl type (94%). The alkenyl-acyl and the alkyl-acyl types were found only 3.8% and 2.3%, respectively. In contrast, 70% of the PLE fraction consisted of the diacyl type and the alkenyl-acyl type accounted for 24%. The alkyl-acyl type (4.3%) was also detected. These results in tongue muscle were similar to those of skeletal muscles in which relatively higher amounts of alkenyl-acyl type were also observed (26.8%). 4. The fatty acid composition of the PLC and PLE fraction was analyzed by gas-liquid chromato-graphy. In the PLC fraction, the fatty acid composition was palmitic acid (34.9%) linoleic acid (18.8%), stearic acid (18.5%), oleic acid (17.0%) and arachidonic acid (10.8%). Docosahexaenoic acid could not be detected in this fraction. This result was different from that of the skeletal muscle, which contained higher amounts of palmitic acid (41.6%) and linoleic acid (30.6%). In the PLE fraction, the fatty acid composition was stearic acid (36.9%), oleic acid (17.9%), docosahexaenoic acid (16.5%), arachidonic acid (10.7%), linoleic acid (9.4%) and palmitic acid (8.6%). The distribution of fatty acids in the PLE of the tongue was similar to that of the skeletal muscle. Significant amounts of docosahexaenoic acid were found in the PLE of the tongue and the skeletal muscle, whereas this fatty acid were hardly detected in the PLC from both tissues. The value of a ratio of saturated fatty acid to unsaturated fatty acid was 1.15 in the PLC and 0.83 in the PLE.
- 札幌医科大学の論文
- 1979-06-01
札幌医科大学 | 論文
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