［原著］Patient Outcome and Reproductive Performance after Conservative Management in Borderline Epithelial Tumors of the Ovary

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Objective. To investigate patient outcome and reproductive performance after conservative treatment for borderline epithelial tumors of the ovary. Methods. A retrospective analysis was undertaken of 77 patients managed for borderline ovarian tumors. Radical surgery included bilateral salpingo-oophorectomy associated with or without hysterectomy (n=42). Conservative surgery was performed with preservation of the uterus and salvage of some ovarian tissue (n=35). No significant differences were found between the two groups in stage and histology of the tumors. Results. Both overall survival and diseasefree survival were not significantly worse in the conservative surgery group compared to the radical surgery group. No significant difference was found in recurrence rate between the groups. In the conservative surgery group, the recurrence rate was significantly higher in the cystectomy group than in the salpingo-oophorectomy group (p=0.011). Among the 35 patients in the conservative surgery group, 26 subsequently attempted pregnancy and 12 (46.2%) achieved a total of 22 pregnancies. Conclusion. Conservative treatment for borderline ovarian tumors is a reasonable option because patient outcome was not significantly affected, although the pregnancy rate was relatively low after this management. The recurrence rate was significantly higher after cystectomy than after salpingo-oophorectomy.