食餌と運動がマウス骨格筋グリコ-ゲン含量に及ぼす影響

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The effects of diet and exercise on glycogen content in skeletal muscle were investigated in adult male ICR mice. After one night fasting and 90 min of swimming, glycogen depletion occurred in both red and white vastus laterahs. After normal mixed diet, the glycogen content increased and reached supercompensated levels. In red vastus, the glycogen content became 3.5 times as much as normal level. However, there was little increase on glycogen content after non-carbohydrate fat diet. When both groups with supercompensated and depleted glycogen contents were run for 30 min at 15 m/min, plasma lactate level in both groups was constant, suggesting exercise intensity was mild. Plasma FFA level in fat fed group was higher than normal mixed diet group before exercise and decreased gradually during exercise. Glycogen content in normal mixed diet group decreased from preexercise level of 25.0 ± 9.6/μmol/g wet wt. in white vastus and 36.8 ± 9.5μmol/g wet wt. in red vastus to 14.5 ± 9.7μmol/g wet wt. and 10.0 ± 4.3μmol/g wet wt. respectively after 30 min of exercise, whereas there was little change on glycogen content in fat fed mice during exercise. These results suggest that in mice performing prolonged mild exercise, a) glycogen is the main energy source in skeletal muscle which has high glycogen content, and b) other substrates like plasma FFA are utilized in skeletal muscle which has depleted glycogen content.
奈良教育大学の論文