マイクロTGGEの応用研究

概要

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A newly developed technology of miniaturized TGGE apparatus, called μTGGE, was further developed to acquire wide applications. Mainly two approaches have been done: improvements in operational problems and development of a truly new application. The former led to the project of pre-cast gel production, which was mostly performed by the company-side, resulting in generation of the first version of this sort. This is believed to be ultimately important for a wide and general use of scientists and researchers in various fields. On the other hand, the latter, mainly carried out by the University-side, has been reaching the stage of building up a new project of developing an automated system for measuring a mutagenic effect of various chemicals named GPMA (Genome profiling-based mutation assay). It is now established that this method is in principle effective. Therefore, the　instrumentation is under way.