Should patients with localized prostate cancer receive primary androgen deprivation therapy?: Commentary
スポンサーリンク
概要
- 論文の詳細を見る
This Practice Point commentary discusses the study by Lu-Yao et al. in which primary androgen deprivation therapy (PADT) was compared with conservative treatment in elderly men with localized prostate cancer. Overall, PADT was associated with worse cancer-specific survival than conservative management; however, in the subgroup of patients with poorly differentiated cancer, PADT was associated with improved cancer-specific survival. Although the authors defined conservative treatment as no definitive treatment during the 180 days after diagnosis, many patients in the conservative treatment group would have subsequently received definite treatments, including surgery or radiation therapy. The results of this study, therefore, do not necessarily demonstrate inferiority of PADT to conservative treatment. Accurate evaluation of the efficacy of PADT is confounded by a number of factors, such as the type of androgen deprivation therapy used. Efforts should be made to reduce the adverse effects of androgen deprivation therapy because a high proportion of patients actively choose this treatment modality as primary therapy.全文公開200905
- 2008-10-28
論文 | ランダム
- 212 ヴィッカーズ硬さ試験の圧痕形状を考慮した材料特性評価(信号処理)(OS.02 : 計測・信号処理・異常診断)
- 表面の法線方向に注目した加工表面異方性の定量評価
- 「支える意思」と「負担力」を維持できる制度へ (特集 社会保障・税一体改革はどこへ)
- ニュース特集 厚生年金・健康保険の適用を非正規雇用者にも拡大--参院予算委員会で菅首相が方針を示す
- 低出生体重児を出産した産婦の周産期の訴えに関する考察