長崎市及び大村市におけるCoxsackie A2 virus感染症の流行例

概要

論文の詳細を見る
An epidemic of febrile illness, which main clinical picture was observed only fever and slight laryngitis without other sever sign, among infancy and children was occurred in Nagasaki and Omura city, Nagasaki prefecture, Japan, during July in 1972. The virus isolation was performed by intracerebrally and intramuscularly injection of 0.02ml of supernatant of samples centrifuged at 10,000 rpm for 20 minutes at 4℃ into suckling mice. Thirty strains from 43 samples of thraot swab collected from 24 cases in Nagasaki city and 19 cases in Omura city, and 19 strains from 24 samples of faces collected from 24 cases in Nagasaki city were isolated. Representative 17 of 49 strains isolated were neutralized by the method of intramuscularly injection into suckling mice with the antiserum against standard strain of Coxsackie A2 virus. The antigen of 4 strains isolated for complement fixation test was prepared from supernatant centrifuged the emulsion made from infected suckling mice muscule. The complement fixing antibody rising was demanstrated in paired sera of 24 cases. It was concluded that an epidemic of febrile illness occurred in Nagasaki and Omura city was caused by Coxsackie A2 virus.
長崎大学熱帯医学研究所の論文
1973-06-00