Treatment of Dipetalonema gracile in Cebus apella by Ivermectin
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概要
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The microfilaricidal effect of ivermectin was studied on Cebus apella infected with Dipetalonema gracile in Paraguay. Nine monkeys were treated with ivermectin at the dosage of 200μg/kg body weight by single subcutaneous injection. The significant reduction in microfilarial count after treatment of ivermectin was recognized (P<0.01). The change of blood picture of 9 monkeys infected with D. gracile following treatment of ivermectin also studied. The total WBC count was found to be significantly increased at 1 day after the treatment. Differential count study showed that neutrophils increased in most monkeys. On the other hand, the significant change in eosinophil and lymphocye count was not observed.
- 長崎大学熱帯医学研究所の論文
- 1991-09-30
長崎大学熱帯医学研究所 | 論文
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