WHO Quality of Life and Its Related Factors in Rheumatoid Arthritis Patients
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概要
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慢性関節リウマチ患者58名を対象に世界保健機構開発のQOL調査票（WHO／QOL-26）を用いて，QOLとその関連要因について検討し，以下の結果を得た． （1）今回の対象者の属性は，日本における慢性関節リウマチ患者のそれに類似するものであった． （2）WHO／QOL-26はその下位次元の一つである社会関係と関連を示さなかった． （3）WHO／QOL-26と有意に関連を示したのは，身体機能，痛み，手術経験の有無，同居者の有無の4要因であった． 以上より，社会関係は他の下位次元との交互作用を介してWHO／QOL-26に関連していると考えられる．また，身体面で痛みの軽減・寛解によって機能改善を図ること，及び生活面で同居者への気兼ねからむしろ同居者無しの方がQOLを高めることが示唆された．Rheumatoid arthritis has total or partial influence on the life situation of patients. A variety of outcome measures are used in evaluating disease activity, therapeutic efficacy, and the quality of life (QOL) in rheumatoid arthritis studies. This study was designed to explore QOL in patients with rheumatoid arthritis in Japan. Fifty-eight rheumatoid arthritis patients (9 male and 49 female, mean age 57.2±14.1) participated as subjects in this study and were interviewed using the World Health Organization's QOL assessment instrument (WHO/QOL-26) by a single interviewer. In addition, simultaneous surveys were made using the Modified Health Assessment Questionnaire (MHAQ) for functional disability, the Visual Analogue Scale for pain (VAS), assessment of patients' understanding of rheumatic disease, and appropriate questionnaires concerning social activities, social support, suffering in life, and demographic characteristics (i.e., age, sex, duration from onset, marital status, presence of other person(s)in household, other illness, having undergone arthritis-related operation(s), holding of physically disabled person's certificate, having hobby(ies), engaged in occupation). Social relationship was the only dimension found not to be correlated with the WHO/QOL-26. Predictors of the overall WHO/QOL-26 were studied by means of multiple regression analysis, with 17 explanatory variables. The factors that had a direct impact on WHO/QOL-26 were MHAQ, VAS, presence of other person(s) in household, and having undergone arthritis-related operation(s). These four factors explained 29.3% of the total variance in WHO/QOL-26 scores. It was suggested by the results that the QOL in rheumatoid arthritis patients is affected especially by pain and by the presence of other person(s) in the household.
- 1999-03-02
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