Structural characterization of N-lignoceroyl (C24:0) sphingomyelin bilayer membranes : A reevaluation
スポンサーリンク
概要
- 論文の詳細を見る
Sphingomyelin (SM) is a membrane lipid and plays important roles in signaling, protein trafficking, cell growth and death. We investigated the structure of hydrated highly asymmetric SM, N-Lignoceroyl (C24:0) SM, bilayers with X-ray diffraction (XRD), simultanous small angle X-ray scattering (SAXS) and wide angle XRD, and SAXS measurements. At temperatures between two endothermic transitions of hydrated C24:0 SM bilayers, the C24:0 SM formed a ripple phase with the ripple periodicity of ~12-14 nm. About 3 month incubation at 277 K induced the formation of a stable phase with a short lamellar spacing of 5.62 nm. Based upon the structures revealed by this study and the phase behavior, we discuss the intermolecular interactions between C24:0 SM molecules in the bilayer membrane.
論文 | ランダム
- はじめに (第3回日本臨床病理学会関東支部例会(特集))
- 新任ソ-シャルワ-カ-必携実践編-1-「アルコ-ル依存症者への援助」
- リンパ節生検最近の知見 (臨床病理の動向(特集))
- 新任ソ-シャルワ-カ-必携-6-「生活保護における社会福祉実践(6)」
- 縱隔洞畸型腫の一剖檢例