Dietary and Physical Activity Effects on Bone Metabolism after Gastrectomy

概要

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The purpose of this study was to investigate how diet and physical activity affect bone density, assessing bone metabolism changes in patients who underwent gastrectomy. The subjects were 10 patients from among 13. Their progress had been monitored for more than 12 months and all participants provided informed consent for this study to be conducted. The study parameters consisted of bone density measurement using and ultrasound method, measurement of bone metabolism makers, the level of daily physical activity by the number of steps walked, and dietary assessment via a questionnaire. As a result, although the OSI (Osteo Sono-Assessment Index) values showed some bone metabolism disorder in the 6th post-operative month, the subjects recovered to the pre-operative condition during and up to the 12th post-operative month. Both bone formation and bone absorption, as indicated by bone metabolism markers (BAP, NTx, and DPD), improved from the 3rd post-operative week to the 6the post-operative month. No correlation was observed linking bone metabolism, body weight, BMI, and physical activity. Intakes of milk, Ca, and Vitamin C, which normally affect bone metabolism disorders, tended to decrease in the bone metabolism risk and disorder groups. Some possible causal factors resulting in bone metabolism disorder include insufficient intakes of calcium and vitamin C and a lack of physical activity.