Theoretical Assessment of FePt Nanoparticles as Heating Elements for Magnetic Hyperthermia
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概要
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FePt magnetic nanoparticles (MNPs) are expected to be a high-performance nanoheater for magnetic hyperthermia because of their high Curie temperature, high saturation magnetization, and high chemical stability. Here, we present a theoretical performance assessment of chemically disordered fcc-phase FePt MNPs. We calculate heat generation and heat transfer in the tissue when an MNP-loaded tumor is placed on an external alternating magnetic field. For comparison, we estimate the performances of magnetite, maghemite, FeCo, and L1_0-phase FePt MNPs. We find that an fcc FePt MNP has a superior ability in magnetic hyperthermia.
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