Bacteriologic features and antimicrobial susceptibility in isolates from orofacial odontogenic infections
スポンサーリンク
概要
- 論文の詳細を見る
Objective. The aim of this study was to obtain information for an effective antimicrobial therapy against orofacial odontogenic infections; such information was obtained from recent bacteriologic features and antimicrobial susceptibility data. Study design. The bacteriology and antimicrobial susceptibility of major pathogens in 163 patients with orofacial odontogenic infections to 7 antibiotics was examined. Results. Mixed infection of strict anaerobes with facultative anaerobes (especially viridans streptococci) was observed most often in dentoalveolar infections, periodontitis, and pericoronitis. Penicillin (penicillin G) was effective against almost all pathogens, although it did not work well against β-lactamase-positive Prevotella. Cefmetazole was effective against all test pathogens. Erythromycin was ineffective against viridans streptococci and most Fusobacterium. Clindamycin exerted a strong antimicrobial activity on anaerobes. Minocycline was effective against almost all the test pathogens. The antimicrobial activity of levofloxacin against viridans streptococci was not strong. Conclusions. An antibiotic that carries out antimicrobial activity against both viridans streptococci and oral anaerobes should be suitable for treatment of dentoalveolar infection, periodontitis, and pericoronitis. Penicillin remains effective as an antimicrobial against most major pathogens in orofacial odontogenic infections. Cefmetazole, clindamycin, and minocycline may be effective against most pathogens, including penicillin-unsusceptible bacteria.
論文 | ランダム
- 3.免疫性神経疾患とアフェレシス(シンポジウム,日本アフェレシス学会第16回関東甲信越地方会抄録)
- 神経疾患に対する免疫グロブリン療法
- 神経疾患に対する免疫グロブリン療法
- 多発性硬化症とアフェレシス(免疫性神経疾患とアフェレシス,新しい展望)
- 偽装国家・日本を改革するために