Increase in stearidonic acid by increasing the supply of histidine to oleaginous Saccharomyces cerevisiae(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)

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概要

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• Increasing concentration of histidine significantly increased stearidonic acid production and cell growth in oleaginous Saccharomyces cerevisiae that has been genetically modified by Δsnf2 disruption, DGA1 and Δ6 desaturase gene overexpression, and LEU2 expression. High concentration of histidine in wild-type transformant and HIS3 expression in Δsnf2 transformant also increased stearidonic acid.

• 公益社団法人日本生物工学会の論文

著者

• Uemura Hiroshi

  Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST)

• Kamisaka Yasushi

  Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST)

• Kimura Kazuyoshi

  Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST)

• Yamaoka Masakazu

  Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST)

関連論文

• Increase in stearidonic acid by increasing the supply of histidine to oleaginous Saccharomyces cerevisiae(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)

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