J161011 カーボンナノチューブによるバイオ分析用構造反応場の高感度化([J16101]マイクロナノメカト口ニクス(1))

概要

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In this study, vertically aligned carbon nanotubes (CNTs) are anticipated as nano/micro structured reaction field for micro bio-analysis. CNTs were synthesized on Silicon substrate using chemical vapor deposition and CNTs reaction field were made of self-organization of CNTs. To evaluate and reveal the optimal CNTs structural dimension and surface characteristics for protein adsorption were evaluated by antigen-antibody reaction using fluorescence analysis. The results showed that proteins tend to adsorb to the tip of CNT and clumping structure of CNTs which has less than 5iLtm distance each other. When the widths of CNTs clumping structure gaps got 1/10, protein adsorption increased 2 times, it means decreasing of distance for diffusion and approaching, and adsorption. Also, protein adsorption increased 2 times more by introducing defects to the CNTs such as plasma irradiation for crystal reforming and HNO3 treatment. Introducing detects on the CNT's walls were let to the expansion of the adsorption site. The sensitivity of this device was 10 times higher than without CNTs and adsorption time was enough in 10 seconds.
一般社団法人日本機械学会の論文
2011-09-11