自己血を応用した骨再生医療(再生医療とアフェレシス)

概要

論文の詳細を見る
Regenerative medicines that use the autologous blood as an ingredient include fibrin glue for stanching and organization adhesion and platelet-rich plasma(PRP)for the purpose of promoting the healing of soft tissue and bone. PRP is a bone regenerative medicine that utilizes autologous blood including growth factors such as transforming growth factor-β(TGF-β),platelet- derived growth factor(PDGF),epidermal growth factor(EGF), and insulin-like growth factor (IGF)from activated platelets, in addition to adhesive factors such as fibronectin, vitronectin, and fibrinogen in the plasma. Furthermore, the preparation of PRP-gel promotes the activation of platelets to release the angiogenetic factors. Recently, we proposed three types of PRP gel; conventional PRP gel for use with transplanting bone, PRP membrane for covering the bone graft region, and PRP sponge to fill the bone socket after tooth extraction. These three PRP gels are clinically useful for oral and maxillofacial surgery. It is believed that the safe regenerative medical treatment enabled through the use of autologous blood will develop further as one of the new fields of apheresis.
日本アフェレシス学会の論文
2006-10-31