Effect of Eleutherococcus senticosus and Its Components on Sex- and Learning-Behaviours and Tyrosine Hydroxylase Activities of Adrenal Gland and Hypothalamic Regions in Chronic Stressed Mice
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概要
- 論文の詳細を見る
Eleutherococcus senticosus and its components, syringin and syringaresinol di-O-glucoside, were studied for their effect on sex behaviours and on acquired conditioned reactions in mice exposed to chronic "hanging stress." Rectal temperature was recorded during exposure to the stress, and adrenal gland weight, tyrosine hydroxylase activity in adrenal gland and hypothalamic regions, and corticosterone content in adrenal gland and serum were measured 24 hr after the final exposure to stress. A water extract from Eleutherococcus senticosus and syringin were shown to protect mice from the stress-induced decreases in sex behaviors and in rectal temperature. Syringaresinol di-O-glucoside protected the animals from the stress-induced decreases in sex behaviours and in rectal temperature, the stress-induced failure of retrieval of memory, and the stress-induced enlargement of adrenal gland. They have no effect however on the stress-induced increase in tyrosine hydroxylase activity in adrenal gland and hypothalamic regions, and on corticosterone contents in adrenal gland and serum.
- 日本生薬学会の論文
- 1985-09-20
著者
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斉藤 博
岡山理大
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IDA Yoshiteru
School of Pharmaceutical Sciences, Showa University
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斉藤 博
岡山理科大学応用物理学科
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Ida Yoshiteru
School Of Pharmaceutical Sciences Showa University
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Ida Yoshiteru
Department Of Pharmacognosy And Phytochemistry Showa University Of Pharmaceutical Sciences
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SHOJI JUNZO
School of Pharmaceutical Sciences, Showa University
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斉藤 博
Department Of Material Science And Technology Nagaoka University Of Technology
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Nishiyama N
Univ. Tokyo Tokyo Jpn
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NISHIYAMA NOBUYOSHI
Experiment Station for Medicinal Plant Studies, Faculty of Pharmaceutical Sciences, University of To
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KAMEGAYA TOSHIHIKO
Experiment Station for Medicinal Plant Studies, Faculty of Pharmaceutical Sciences, University of To
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IWAI AKIHIKO
Experiment Station for Medicinal Plant Studies, Faculty of Pharmaceutical Sciences, University of To
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SAITO HIROSHI
Experiment Station for Medicinal Plant Studies, Faculty of Pharmaceutical Sciences, University of To
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SANADA SHUICHI
Department of Pharmacognosy, School of Pharmaceutical Sciences, Showa University
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SHOJI JUNZO
Department of Pharmacognosy, School of Pharmaceutical Sciences, Showa University
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Kamegaya Toshihiko
Experiment Station For Medicinal Plant Studies Faculty Of Pharmaceutical Sciences University Of Toky
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Iwai A
Chita Kousei Hospital Aichi Jpn
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