胸腺腫の治療戦略-治療方針の確立と予後(特別講演 III, 第154回名古屋市立大学医学会例会)

概要

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Thymoma is a relatively rare tumor and this neoplasm arises from thymic epithelial cells with non-neoplastic T lymphocytes at varying degrees. Myasthenia gravis is a common complication in thymoma patients. Surgical resection has been advocated as the principal treatment and completeness of resection has been considered to be the most important determinant of long-term survival. However, in advanced thymomas, treatment strategy has not been established yet. Since Masaoka has suggested Masaoka stage classification, we have performed many studies about strategy for thymoma in our department. In early-staged thymomas, extended thymothymomectomy is a standard operation. We have adapted the technique of video-assisted thoracoscopic surgery for thymoma. In advanced-staged thymomas, we have demonstrated the efficacy of steroid pulse therapy. In thymomas with pleural disseminated nodules, we have demonstrated the efficacy of macroscopic total resection of the disseminated nodules. To establish treatment strategy for thymomas, further studies to be accumulated are necessary.
2010-12-01