Out-of-Equilibrium versus Dynamical and Thermodynamical Transitions for a Model Protein(Frontiers in Nonequilibrium Physics-Fundamental Theory, Glassy & Granular Materials, and Computational Physics-)

スポンサーリンク

概要

• 論文の詳細を見る

• Equilibrium and out-of-equilibrium transitions of an off-lattice protein model have been identified and studied. In particular, the out-of-equilibrium dynamics of the protein under-going mechanical unfolding is investigated, and by using a work fluctuation relation, the system free energy landscape is evaluated. Three different structural transitions are identified along the unfolding pathways. Furthermore, the reconstruction of the the free and potential energy profiles in terms of inherent structure formalism allows us to put in direct correspondence these transitions with the equilibrium thermal transitions relevant for protein folding/unfolding. Through the study of the fluctuations of the protein structure at different temperatures, we identify the dynamical transitions, related to configurational rearrangements of the protein, which are precursors of the thermal transitions.

• 2010-07-27

著者

• IMPARATO Alberto

  Department of Physics and Astronomy, University of Aarhus

• IMPARATO Alberto

  Dept. of Physics and Astronomy, University of Aarhus

• LUCCIOLI Stefano

  Istituto dei Sistemi Complessi, CNR

• TORCINI Alessandro

  Istituto dei Sistemi Complessi, CNR

• Luccioli Stefano

  Istituto Dei Sistemi Complessi Cnr:infn Sez. Firenze:csdc

• Imparato Alberto

  Dept. Of Physics And Astronomy University Of Aarhus

• Torcini Alessandro

  Istituto Dei Sistemi Complessi Cnr:infn Sez. Firenze:csdc

• TORCINI Alessandro

  Istituto dei Sistemi Complessi, CNR:INFN, Sez. Firenze:CSDC

• Luccioli Stefano

  Istituto dei Sistemi Complessi, CNR:INFN, Sez. Firenze:CSDC

関連論文

• Out-of-Equilibrium versus Dynamical and Thermodynamical Transitions for a Model Protein(Frontiers in Nonequilibrium Physics-Fundamental Theory, Glassy & Granular Materials, and Computational Physics-)
• Current Fluctuations in Systems with Diffusive Dynamics, in and out of Equilibrium(Frontiers in Nonequilibrium Physics-Fundamental Theory, Glassy & Granular Materials, and Computational Physics-)

スポンサーリンク