1612 衝撃波による脂質二重層膜の特性変化に関する分子動力学計算(S22 ドラッグデリバリーシステムと流体力学,21世紀地球環境革命の機械工学:人・マイクロナノ・エネルギー・環境)

概要

論文の詳細を見る
We investigate the effect of shock wave parameters on characteristic changes of a lipid bilayer by using molecular dynamics simulations. The action of shock wave is modeled by a shock wave impulse that is implemented by adding a momentum to water molecules in a region of the system calculated. The various waveforms are generated by changing the size of the region. From the results of velocity and density profiles across the system, it is found that the waveform becomes steep when the small sized region is used in an impulse condition. The shock wave induces water penetration into the hydrophobic region of the bilayer as in our previous study. The number of water molecules penetrated becomes small with increasing the size of the region; this implies that using steep waveform shock wave is favorable to the water penetration for the shock wave impulse conditions studied here.
2008-08-02