＜Luncheon Seminar＞Current concepts in Alzheimer's disease

スポンサーリンク

概要

• 論文の詳細を見る

• Like my presentation, this article focuses exclusively on the role of the amyloid ß protein in Alzheimer’sDisease. I fi rst provide an overview of the research fi ndings that have made Aß, more specifi cally Aß42, a compellingtherapeutic target for AD that is being pursued by virtually all pharmaceutical companies. I then discuss specifi capproaches to Aß-centered therapy. It is widely believed that the best way to manage AD will be through preventivetherapy. To implement preventive therapy, it is critically important to be able to identify normal subjects who areat imminent risk for AD. In the last part of this article, I review recent evidence indicating that the measurement ofAß40 and Aß42 in plasma may be useful for identifying those normal subjects who will develop AD.

著者

• Younkin Steven

  Department Of Neuroscience Mayo Clinic College Of Medicine

• Younkin Steven

  Department Of Neuroscience Mayo College Of Medicine

関連論文

• ＜Symposium IV＞Genetic variation in PCDH11X is associated with susceptibility to late onset Alzheimer's disease
• ＜Luncheon Seminar＞Current concepts in Alzheimer's disease
• The APP and PS1/2 mutations linked to early onset familial Alzheimer's disease increase the extracellular concentration of Aβ1-42(43)

スポンサーリンク