インスリン依存型糖尿病における神経障害に関する研究 : F波伝導検査およびsympathetic skin response(SSR)測定の意義

概要

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To evaluate the significance of SSR and F wave in IDDM patients with neuropathy, we examined these parameters, RR interval variations and peroneal nerve conduction velocity in IDDM patients with (n=22) or without (n=23) diabetic complications and 23 healthy controls. In the IDDM patients without complications, the ampulitude and latency of SSR were significantly decreased. The RR interval was not significantly different between the IDDM patients without complications and controls. The latency, nerve conduction velocity and the ratio of latency to body length of the F wave were significantly lower in the IDDM patients than healthy controls. In the IDDM patients, there was a linear correlation between the mean HbA_<1c> for 6 year of diabetes and the amplitude of SSR, the latency, amplitude, latency per height of the F wave. These results suggest that SSR and F wave may be useful for the early detection of diabetic neuropathy in IDDM patients.
東京女子医科大学の論文
1996-07-25