農村に於ける鉤虫症の臨床的研究

概要

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Clincal studies of ancylostomiasis, particularly the anemic symptoms that attend it, were carried out in 482 patients seen at Satte Agricultural Cooperative Hospital in Saitama Prefecture. These patients were examined 5 weeks before and after the administration of an anthelmintic. The incidence of ancylostomiasis is still very high in the farming community, especially among the grownups, The chief symptoms consisted of epigastric fullness and discomfort, belly ache, ennui, short breath anc dizziness. An iron preparation was the most effective in the treatment of anemia that occurred after expelling the worms, followed by a kidney extract. It was found that those receiving no medication had had anemia for quite a long time. There was a slight increase in leukocyte count, which was presumed to be due to the increase in eoginophil cell count. Liver function, which showed a slight disturbance in ancylostomiasis, was found to improve rapidly as soon as the worms were expelled. A high percentage of patients had positive fecal occult blood test, but they soon became negative after the worms were expelled. In view of these findings, the need for early diagnosis and the administration of an anthelmintic, coupled with an effective remedy for anemia, to be given to all the outpatients should be emphasized, though it goes without saying that the organization of a compaign for the prevention of hookworm infestation in imperative.
千葉大学の論文