術後空腸潰瘍の臨床ならびに病理学的研究
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概要
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The author tried to find out the histopathologic character of 19 cases of postoperative jejunal ulcer, based on the clinical and experimental research. By this investigetion, clinically the same results, which were reported by other authors, were obtaned. The only difference was that the patients who underwent the first operation at their early age had tendency to get jejunal ulcer, and that also in this group the reaction of gastric juice to caffeine tended to have prolonged effect. By the histopathologic investigation in ourv cases, ulceration of the jejunum in acute and subacute stage formed gradual deepening .as much as gastroduodenal ulcer. But what was different from the latter was that jejunal ulcer had weak proliferation of the granulation tissue in spite of the inflammatory zone at the bottum of ulcer invased to the wide regions. It appeared that plasma cells and eosinophiles were exceptionally overproliferated and infiltrated in the inflammatoy zone of jujenal ulcer. The demarcating inflammation at the base of jejunal ulcer was not so remarkable as the weaked granulation tissue. But in the case where the major omentum adhered to the bottum of ulcer, the demarcating inflammation had tendency to be severe. The author could not find "deeper demarcating inflammation" in all cases. In additions the thickening of the wall of the vessels and arteritis at the base of ulceration were very slight. In conclusion, this ulcerated area increased gradually in depth without the stratified structure and the deeper demarcating inflammation, and fixed after scaring of the inflammatory bottum of ulcer. This histopathologic findings indicate very weak resistance of the ulcer to the continous effect of gastric juice, so that these ulcers have more posibility of perforating occasionally. Based on the above observation, internal treatments to these ulcers were not hopeful, and the radical operation in their cases was advisable. Among the surgery for these ulcers, the author believes that gastrectomy by Nakayama's method is the safest and simplest.
- 千葉大学の論文
- 1959-09-28
著者
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- 術後空腸潰瘍の臨床ならびに病理学的研究
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