放射性コバルト(Co^<60>)近接照射の子宮頸部癌に及ぼす肉眼的,組織学的変化
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For the purpose of investigating the effects of contact irradiation with a small source of radioactive cobalt (Co^<60>) on cancer of the cervix uteri, 32 cases of the 41 cases of cancer of the cervix uteri of the papillary form were given cobalt treatment, and the rest of the cases, 9 cases, were given radium treatment, which served as controls. In order to evaluate the effects of treatment in terms of the quantity of emanation, cancerous growths were examined both macroscopically and microscopically several times before, during and after the treatment. 1. Having been subjected to contact irradiation of Co^<60> of a total of about 3,840 millicurie hours, the cancerous tissue showed sudden destruction, contraction in size, disappearance and cicatrization in gross appearance. Histologic sections showed disturbance of the stroma, with attendant changes in the vessels, and secondary proliferation of the connective tissue, in addition to marked degeneration of the cancer cells. The cancer cells, which had disappeared, were replaced by the connective tissue 1 month after treatment. 2. There was no essential difference between the changes brought about by radium and cobalt irradiation. 3. The behavior of the eosinophile leukocytes and argyrophil fibrils was studied in terms of the quantity of emanation. It was shown that the former might be related in some way to retrogression of the cancerous growth, and that the latter had comparatively strong resistance to irradiation, for they were still idntified in necrotic area, thought they had become thicker or finer, or was broken to pieces as a result of irradiation. 4. The degree of ripeness of the cancerous tissue may vary from one location to another in one cancerous growth. This indicates that it is difficult to advance any valid discussion on the relation of the degree of ripeness of the cancerous tissue to radio sensibility merely on the basis of microscopic findings on a small experimental section.
- 千葉大学の論文
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関連論文
- 7)放射性コバルト(Co^)及びラジウム(Ra)近接照射による子宮頸部癌の組織学的変化(第354回千葉医学会例会産婦人科分科会)
- 放射性コバルト(Co^)近接照射の子宮頸部癌に及ぼす肉眼的,組織学的変化
- 31. 子宮頸癌に対する制癌剤のイオントホレーゼ療法(第34回千葉医学会総会講演要旨)