自律神経機能と胸腔内操作時の反射性障害に関する臨床的研究

概要

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Respiratory and circulatory disturbances that occur in intrathoracie operation are closely related to the functioning of the autonomic nerves. The fall in blood pressure which takes place in intrathoracic operation was frequently seen in persons with vagotonia or vegetative-labile, but was rare in those with sympatheticotonia or normally functioning autonomic nerves. Mechanical stimulation of the hilus and the bronchial stump often caused apnea or irregular breathing in persons with vagotonia or vegetative-labile, but this phenomenon was scarecely seen in persons with sympatheticotonia or normally functioning autonomic nerves. The stimulus applied to these parts did not cause any changes in electrocardiograms. When stimulus was applied to the pericardium, electrocardiograms of persons with vagotonia or vegetative-labile showed ventricular flutter, nodal rhythm, sinus arrhythmia, partial block and ventricular extrasystole, though there was no disturbance of breathing. Administration of a parasympathetic blocking agent may be effective in preventing the occurrence of above-mentioned respiratory and circulatory disturbances in intrathoracic operation.
千葉大学の論文
1959-01-28