抗腫瘍性物質gancidinの研究 : 生産株の菌学的考察並びに有効物質の生産及び有効分劃の単離精製について

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概要

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• The mycological study of S. AAk-84 was carried out. Among known species of streptomyces which are listed in Waksman and Lechevalier's book "Actinomycetes and their Antibiotics," four species, i. e. S. exfoliatus, S. gelaticus, S. rutgersensis and S. halstedii proved to have some resemblances to S. AAk-84. By the detailed morphological studies, cultural characteristics and physiological aspects of the strain AAk-84, it became evident that the strain could be differentiated from those species and tentatively named as S. gancidicus. When tested in routine manner, complex organic nitrogen compound such as meat extract or peptone was required for the production o' gancidin. Among six carbon sources tested, starch supported the most prominent yield of gancidin followed by maltose and glycerol. Six active fractions which had varying physicochemical and biological properties were so far obtained and their isolation and natures are described.

• 千葉大学の論文

著者

• 鈴木 正己

  吉原病院

• 鈴木 正己

  千葉大学腐敗研究所

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• 抗腫瘍性物質gancidinの研究 : 生産株の菌学的考察並びに有効物質の生産及び有効分劃の単離精製について

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