小児ケトージスの臨牀的研究 : 第2編 数種疾患に於けるケトージスの観察
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Studies made on ketone bodies in the bloods of infants and children with dysentery, ekiri, auto-intoxication and Japanese encephalitis have revealed that all the patients examined show .a marked tendency to ketosis. It was worthy of note that, of the dysentery patients examined, those in the age group 3-8 showed a higher level of ketone bodies as compared with other age groups. The level obtained with 23 dysentery patients was 14.01 ≧ m ≧ 6.69 mg/dl, which seemed to increase with the progress of the disease, reaching the maximum a few days after onset of the disease. Though the level obtained with ekiri patients, which was 29.34 ≧ m ≧ 14.04 mg/dl, was higher than that prevailing among dysentery patients, it was nearly equal to the level obtained with dysentery patients in the age group 3-8. In patients with Japanese encephalitis, the increase in the formation of ketone bodies both in the blood and spinal fluid was proved. In 3 among 8 patints examined, ketone bodies found in the spinal fluid were of higher concentration than those found in the blood. The prognosis of the patients with this phenomenon, which is presumed to be due to the promotion in permeability of the meninges, was poor in most cases. There was no uniform relation between the concentration of ketone bodies, the cell level in the spinal fluid and complement fixation reaction. Although the administration of liquid glucose for the treatment of dysentery and ekiri showed also an effect on the control of ketosis, the amount sufficient for inducing this action was 4.0 g per kg of body weight in 24 hours, the dose of 2.0 g per kg of body weight having resulted in a rise of the level of ketone bodies again because of the lack of sugar after a temporary fall. It is desirable that this large amount of liquid glucose be administered in instalments, for the wholesale injections cause glycosuria, making its full utilization impossible. It is also desirable that liquid glucose be administered in combination with saline solution, as it tends to cause dehydration.
- 千葉大学の論文
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関連論文
- 29)十二指腸臣大症の1例(第360回千葉医学会分科会,第55回日本小児科学会千葉地方会総会)
- 小児ケトージスの臨牀的研究 : 第2編 数種疾患に於けるケトージスの観察
- 小児ケトージスの臨床的研究 : 第1編 ケトン食に依るケトージスの観察