耳下腺唾液分泌に関する研究

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The amounts, hydrogen ion concentrations, viscosity, specific gravity and ptyalin levels of the saliva collected for thirty minutes after stimulating the parotid glands were measured in 129 normal persons (129 normal parotids) and 118 patients (129 morbid parotids), and the results were interpreted on the basis of the theory of statistical inference. Stimulus was applied by dripping 1 cc of the aqueous solution of 1/4 mol tartaric acid on the tongue at ten minutes' intervals. A study on the relation between the results of the above experiments and sialographic appearances of the parotids was also performed. 1) There was no significant change in the saliva secretion by a parotid gland attributable to the difference in seasons-i.e. between the period from May to October and the period from November to April. 2) Both the amounts and hydrogen ion concentrations were larger in persons younger than 19 years of age than in any other age groups, while they showed no essential difference between persons in their 20 s and 30 s than those over 40 years of age, 3) There was a close relation between the amounts of saliva secretion and the following 5 types of sialographic shadows of the parotid glands as classified by Prof. Kitamura-homogeneous shadow (type I), lobulated shadow (type II), dappled shadow with small spots (type II[), dapped shadow with large spots (type IV) and shadowless (type V). The secretion increased in amounts in the order as indicated above. 4) In cases of acute inflammation, there were a decrease in amounts, a fall in ptyalin levels and an increase in specific gravity. 5) In cases of sialoangiectasis, there were a decrease in amounts, a fall in ptyalin levels and an increase in hydrogen ion concentrations. 6) In cases of tumors of the parotid gland, there were decreases in amounts and hydrogen ion concentrations. 7) In cases where a parotid gland of one side had been removed, there was no increase in the amounts of saliva secretion by the residual gland; on the contrary, there were decreases in amounts and hydrogen ion concentrations and a rise in ptyalin levels; and many of them demonstrated shadows of types I and II which are assumed to indicate normal parotids. 8) There was no change in the functioning of the parotid gland on the same side as the ear which had had its inner and middle ears radically operated on. 9) In cases of xerostomia, there were decreases in amounts and hydrogen ion concentrations and arise in ptyalin levels; many of those cases that showed objected symptoms demonstrated shadows of types III and IV which are assumed to indicate morbid parotids. 10) In cases of atrophic rhinitis, there was no change in the nature of saliva secreted by the parotids. 11) The viscosity of the saliva secreted by the parotid gland has been of no significance.
千葉大学の論文
1957-01-28

耳下腺唾液分泌に関する研究

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