人唾液の分泌型,非分泌型について
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概要
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It wad found by Schiff and Sasaki that there existed two types in saliva as to the secretion of blood group substances, designated as secretor and non-secretor, and the finding was confirmed by many workers. It was also shown that there are some instances in which the secretion of group substances is so weak that differentiation of these types appears difficult. Meanwhile, Ueyama discovered a very significant and important fact that in some cases of domestic fowl a precipitin (anti-T) can be found in serum which reacts with the saliva of nons-ecretor, but not with that of secretor. We have performed researches into the relation of the reaction of the A-B-O blood group, system to that of the T system in a number of such doubtful cases in which the secretion of A-B-O group substances were particularly weak. The results of our experiments have shown that in such cases the differentiation of secretor and non-secretor can be made in general by the usually used agglutination inhibiting test with A-B-O system, but that a clear-cut differentiation would be accomplished when the T-anti-T precipitin reaction is employed. It was reported and has been generally accepted that in salive of non-secretor some partial group antigens, through in a minimum amount, can be demonstrated. We have done studies to see how the partial group antigens are secreted in saliva of secretor as well as of non-secretor, using particularly the antisera obtained by immunization with saliva and not with red blood cells as far as possible. Since the immunization with red blood cells develops sometimes such agglutinins which are not inhibited by saliva antigens. The results are reported in part 2 of this paper.
- 千葉大学の論文
- 1955-05-28