Value of Convex-Type ST-Segment Elevation and Abnormal Q Waves for Electrocardiographic-Based Identification of Left Ventricular Remodeling in Hypertrophic Cardiomyopathy
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概要
- 論文の詳細を見る
Several studies have demonstrated that the natural course of hypertrophiccardiomyopathy can be variable, often unpredictable with high morbidity andmortality. Therefore, screening for potential cases and periodical evaluation of affectedpatients is compelling. The purpose of our study is to assess a relationship of theelectrocardiographic finding of ST-segment elevation and/or abnormal Q waves withthe development of left ventricular enlargement and wall motion abnormalities in theechocardiography and to propose these findings as a sign of left ventricular remodelingin patients with hypertrophic cardiomyopathy. We enrolled 110 patients withhypertrophic cardiomyopathy. Standard echocardiography and 12-leadelectrocardiograms were analyzed. After initial evaluation, follow up was conductedwith a mean interval of 20.3 months. In the electrocardiograms we found ST-segmentelevation in 43.6% and abnormal Q waves in 18.1%; and left ventricular enlargementin 12.7% and wall motion abnormalities in 21.8% in the echocardiograms. Threedifferent patterns of ST-segment elevation were acknowledged: concave (13.6 %),straight (16.3 %) and convex (13.6%). There was a close relationship between theelectrocardiographic finding of convex ST-segment elevation and/or abnormal Q wavesand the occurrence of left ventricular enlargement and/or wall motion abnormalities inthe echocardiograms with a sensitivity of 62% and a specificity of 85%. However, thestraight and concave-type ST-segment elevation showed a less significant relationshipwith the echocardiographic findings. This study suggested that the electrocardiographicfinding of convex ST-segment elevation and abnormal Q waves could be valuable fordetection of disease progression in patients with hypertrophic cardiomyopathy.
- 神戸大学の論文
著者
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HIRATA Ken-ichi
Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate Schoo
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Kawai Hiroya
Division of Cardiovascular and Respiratory Medicine Department of Internal Medicine, Kobe University
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Hirata K
Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School
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Furuki Maki
Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School
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ONISHI Tetsuari
Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate Schoo
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Hirata Kenichi
Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School
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Furuki Maky
Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate Schoo
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Hirata Ken-ichi
Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School
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Ohnishi Tetsuari
Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School
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Onishi Tetsuari
Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School
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Kawai Hiroya
Division Of Cardiovascular And Respiratory Medicine Department Of Internal Medicine Kobe University
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Kawai Hiroya
Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School
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Kumagai Hiroyuki
Department Of Cardiovascular And Respiratory Medicine Kobe University Graduate School Of Medicine
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Kumagai Hiroyuki
Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School
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Hirata Kenichi
Division Of Cardiovascularmedicine Kobe University Graduate School Of Medicine
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Kawai Hiroya
Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School
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Kumagai Hiroyuki
Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School
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Onishi Tetsuari
Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School
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Kumagai Hiroyuki
Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School
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Onishi Tetsuari
Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School
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Kumagai Hiroyuki
Department Of Internal Medicine Division Of Cardiovascular Medicine Kobe University Graduate School Of Medicine
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Onishi Tetsuari
Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School Of Medicine
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HIRATA Ken-ichi
Division of Cardiovascular and Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine
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Kawai Hiroya
Division of Cardiology, Himeji Cardiovascular Center
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