恙蟲病々毒接種ノ抗體産生機能ニ及ボス影響 : 第3回報告 これら菌凝集素ニ關スル研究
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It was made clear in the author's first and second Reports that the injection of Tsutsugamushi virus raises considerably the normal power of agglutinating bacillus typhosus and b. paratyphosus A and B, and that further the injection raises the production of these three bacilli immune agglutinin. The purpose of the present experiments in rabbits was not only to find out what relation, if any, there is between the injection of Tsutsugamushi virus and the agglutininproduction of vibrio cholerae, whose group is bacteriologically quite different from that of b. typhosus and b. paratyphosus, but also to make clear that the injection of Tsutsugamushi virus raises selectively only the production of b. typhosus and b. paratyphosus agglutinin. The following are the conclusions: 1) The injection of Tsutsugamushi virus raises the normal power of agglutinating vibrio cholerae. The injection of variola virus used as a control also raises the normal power of agglutinating this vibrio, but the injection of Tsutsugamushi virus raised it to a higher degree. 2) The normal power of agglutination is highest about the 7th day and the next highest period the 12th day after the injection of Tsutsugamushi virus. This is almost in accordance with the results of the first and second Reports, but the degree of raising of the normal power of agglutinating this vibrio is considerably low as compared with that of the normal power of agglutinating b. typhosus and b. paratyphosus. 3) The injection of Tsutsugamushi virus also raises the production of vibrio cholerae immune agglutinin. The results on injecting variola virus are similar to the above, but the injection of variola virus raises the production in a lower degree. 4) The degree of raising of the production of vibrio cholerae immune agglutinin by injecting Tsutsugamushi virus is much lower than that of the production of b. typhosus and b. paratyphosus immune agglutinin, and the period of the high power of the vibrio immune agglutinin is shorter that of the later. 5) The facts above mentioned show that the special and considerable raising of the production of agglutinin by inoculation with Tsutsugamushi virus seems to be observed selectively only on b. typhosus and b. paratyphosus.
- 京都府立医科大学の論文
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