Quantitative light-induced fluorescence clinical study on how fluoride dentifrice affects the progression of white spot lesions

概要

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We attempted to determine the efficacy of fluoride dentifrice on remineralization of white spot lesions using quantitative light-induced fluorescence (QLF). The study was approved by the Ethics Committee at Osaka Dental University Hospital prior to recruiting patients. All subjects gave their informed consent and 129 patients completed the clinical study. They were allocated randomly to the fluoride group and the placebo group, with 65 subjects using fluoride dentifrice containing 950ppm fluoride (NaF), and 64 using placebo dentifrice without fluoride. The patients were required to brush their teeth twice a day using the assigned dentifrices for one year. The remineralization effects of the fluoride and placebo dentifrices were evaluated by three QLF parameters: ΔQ (%・mm^2), mineral loss; S (mm^2), lesion area; and ΔMax (%), maximum lesion depth at three, six and twelve months recalls after the baseline examination. We concluded that the fluoride dentifrice improved remineralization of the clinical white spot lesions.
大阪歯科学会の論文