Elevated Blood Pressure, Decreased Heart Rate Variability and Incomplete Blood Pressure Recovery after a 12-hour Night Shift Work
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概要
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Shift work has been associated with increased risk of cardiovascular disease. This study was designed to determine the hemodynamic effects of 12-hour (12-h) shifts, and changes in blood pressure (BP) and heart rate variability (HRV) during 36h rest time following 12-h shifts. Fifteen male shift workers with a mean age of 32.9yr were recruited from a semiconductor factory. Ambulatory BP (AmBP) monitoring was performed for a total of 48h for each participant. Six workers were monitored for 48h by Holter electrocardiogram on both the day and night shifts. Paired self-comparison was used to estimate the difference between two hourly measurements of 12-h BP, HR, and HRV using the same timetable intraindividually. We also applied mixed models to estimate the effects of 12-h shifts on the delayed recovery of BP and heart rate (HR) in six workers who completed 96-h AmBP monitoring, including a 48-h night shift-rest period and another day shift period. Results showed that 12-h night shift work gave a persistently elevated systolic and diastolic BP (SBP and DBP) and HR, and decreased HRV compared to 12-h day shift work with the corresponding resting time. In addition, there was delayed SBP and DBP recovery on the first 12-h rest time in night shift workers, which was further demonstrated on the second 12-h rest time after adjustment for possible confounders through mixed models. In conclusion, 12-h night shift work may elevate BP and HR and decrease HRV. It is also associated with delayed BP recovery.
- 社団法人日本産業衛生学会の論文
著者
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Chen Ming-fong
台湾
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Chen Ming-fong
Department Of Cardiology National Taiwan University Hospital
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Hwang Wen-chang
Institute Of Occupational Medicine And Industrial Hygiene College Of Public Health National Taiwan U
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Wang Jung-der
Department Of Internal Medicine National Taiwan University Hospital:institute Of Occupational Medici
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Wang Jung-der
Department Of Internal Medicine National Taiwan University Hospital:department Of Environmental And
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SU Ta-Chen
Department of Internal Medicine, National Taiwan University Hospital
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LIN Lian-Yu
Department of Internal Medicine, National Taiwan University Hospital
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BAKER Dean
Center for Occupational and Environmental Health, University of California at Irvine
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SCHNALL Peter
Center for Occupational and Environmental Health, University of California at Irvine
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CHEN Chen-Fang
Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan
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Su Ta-chen
Department Of Cardiology National Taiwan University Hospital
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Su Ta-chen
Department Of Internal Medicine National Taiwan University Hospital:department Of Environmental And
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Baker Dean
Center For Occupational And Environmental Health University Of California At Irvine
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Lin Lian-yu
Department Of Internal Medicine National Taiwan University Hospital
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Schnall Peter
Center For Occupational And Environmental Health University Of California At Irvine
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Chen Chen-fang
Institute Of Occupational Medicine And Industrial Hygiene College Of Public Health National Taiwan U
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Lin Lian-Yu
Department of Internal Medicine (Division of Cardiology), National Taiwan University Hospital, National Taiwan University College of Medicine
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