Main Pulmonary Arterial Distensibility : Different Presentation Between Chronic Pulmonary Hypertension and Acute Pulmonary Embolism
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概要
- 論文の詳細を見る
Background The main pulmonary arterial (PA) distensibility in patients with pulmonary hypertension (PH) and pulmonary embolism (PE) is uncertain. Methods and Results We enrolled 45 patients with echocardiographic signs of PH and without imaging evidence of PE, and another 45 who were found by multidetector-row computed tomography to have PE. Fifty normal patients served as a control group. The PA distensibility was calculated from the change in main PA diameter between diastole and systole, as the maximal systolic diameter minus the minimal diastolic diameter divided by the minimal diastolic diameter. The PA distensibility is lowest in PH (6.0±2.7%), followed by PE (12.9±3.4%) and then the normal controls (25.9±5.7%). Statistical analysis of data obtained from patients with PE or PH reveals that a PA distensibility of >8.3% could be used to identify PE with a sensitivity of 83% and a specificity of 82%. After a 3-month anticoagulation, 22 of 45 PE patients had complete resolution of thrombus: 23 had residual thrombus. The PE patients, regardless of residual thrombus presence, had significant improvement of PA distensibility after a 3-month anticoagulation, although the diameters of main PA did not shrink. Conclusion PA distensibility is a method to distinguish acute PE from chronic PH.
- 社団法人日本循環器学会の論文
- 2008-08-20
著者
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CHIOU Kuan-Rau
Division of Cardiology, Department of Internal Medicine, Kaohsiung Veterans General Hospital
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Lee Chiu-yen
Cardiovascular Center Department Of Internal Medicine Kaohsiung Veterans General Hospital
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Lin Shih-kai
Division Of Cardiology Department Of Internal Medicine Kaohsiung Veterans General Hospital
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Chiou Kuan-rau
Division Of Cardiology Department Of Internal Medicine Kaohsiung Veterans General Hospital
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Chiou Kuan-Rau
Cardiovascular Medical Center, Kaohsiung Veterans General Hospital
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Hsiao Shih-Hung
Cardiovascular Medical Center, Kaohsiung Veterans General Hospital
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Lin Shih-Kai
Cardiovascular Medical Center, Kaohsiung Veterans General Hospital
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Hsiao Shih-hung
Division Of Cardiology Department Of Internal Medicine Kaohsiung Veterans General Hospital
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Yang Shu-hsin
Cardiovascular Center Department Of Internal Medicine Kaohsiung Veterans General Hospital
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Wu Den-Ko
Cardiovascular Center, Department of Internal Medicine, Kaohsiung Veterans General Hospital
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Chang Shu-Mei
Cardiovascular Center, Department of Internal Medicine, Kaohsiung Veterans General Hospital
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Chang Shu-mei
Cardiovascular Center Department Of Internal Medicine Kaohsiung Veterans General Hospital
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Wu Den-ko
Cardiovascular Center Department Of Internal Medicine Kaohsiung Veterans General Hospital
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- Main Pulmonary Arterial Distensibility : Different Presentation Between Chronic Pulmonary Hypertension and Acute Pulmonary Embolism
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