108(P-50) Juniperus属植物のフェノール性成分の構造と生物活性(ポスター発表の部)
スポンサーリンク
概要
- 論文の詳細を見る
In the course of our phytochemical studies of North American useful plants, we investigated the chemical constituents in Juniperus plants. Genus Juniperus belongs to family Cupressaceae and it comprises about 70 species distributed in the Northern Hemisphere. Juniperus communis is a familiar species with the characteristic flavor of distilled liquor gin. In this report we present the structural determination and biological activities of phenolic components of J. communis var. depressa and J. occidentalis collected in Oregon, U.S.A. From the methanolic extracts of the two Juniperus plants, 22 flavonoids (1-22), 15 neolignan (lignan) glycosides (23-37) and 17 phenylpropanoids (phenylethanoids) (38-54) were isolated and thier structures were established on the basis of spectral and chemical evidence. Among them, biflavonoids (1, 2), flavan glucosides (6, 7), neolignan glycosides (23, 24, 30-32, 35), phenylethanoids (38, 39) and phenylpropanoids (41, 48) were new compounds. Compounds 1 and 2, obtained from J. communis var. depressa, were confirmed to be atropisomers of cupressuflavone 4'-O-β-D-glucopyraonoside. The absolute stereochemistries of 1 and 2 were determined to be aR and aS, respectively, by CD spectra. Although cupressuflavone has been isolated from various gymnosperms, 1 and 2 are the first instance of its glycosides. The inhibitory activities of some isolated compounds on the Maillard reaction and lipid peroxide formation were examined. As a result, (-)-catechin (10) and (+)-epicatechin (11) strongly inhibited AGEs formation in the Maillard reaction. Similarly, some flavonoids showed moderate inhibitory activities on the Maillard reaction and lipid peroxide formation.
- 天然有機化合物討論会の論文
- 2004-10-01
著者
-
松浦 信康
岡山理大・理
-
田中 稔幸
岐阜薬大薬
-
飯沼 宗和
岐阜薬大薬
-
田中 稔幸
岐阜県保環研
-
田中 稔幸
Department Of Pharmacognosy Gifu Pharmaceutical University
-
松浦 信康
岡理大理
-
邑田 裕子
摂南大薬
-
Tanaka N
Department Of Pharmacology School Of Pharmaceutical Sciences Mukogawa Women's University
-
Tanaka Naoko
武庫川女子大学 薬学部薬理学
-
Murata H
Faculty Of Pharmaceutical Sciences Setsunan University
-
稲冨 由香
摂南大薬
-
飯田 直樹
摂南大薬
-
稲田 昭
摂南大薬
-
中西 勤
摂南大薬
-
飯沼 宗和
岐阜薬科大学
-
飯沼 宗和
Department Of Pharmacognosy Gifu Pharmaceutical University
-
中西 勤
摂南大学薬学部
-
中西 務
Faculty Of Pharmaceutical Sciences Setsunan University
-
稲田 昭
摂南大学薬学部
-
Tanaka N
School Of Pharmaceutical Sciences Mukogawa Women S University
-
飯沼 宗和
岐阜薬大
-
稲田 昭
Faculty Of Pharmaceutical Sciences Setsunan University
-
Nishimata Toyoki
R & D Division Daiichi Sankyo Co. Ltd.
関連論文
- 43(P-5) プロアントシアニジンの化学 : 系統的オリゴマーの合成ならびに構造-活性相関とその応用(ポスター発表の部)
- P-58 グネツム科およびウェルウィッチア科植物のスチルベノイドと生理活性(ポスター発表の部)
- P-17 フタバガキ科植物のスチルベンオリゴマーの構造と生物活性(ポスター発表の部)
- P-1 フタバガキ科植物のスチルベンオリゴマーの構造回転異性を有するshoreaketoneの構造とスペクトル特性(ポスター発表の部)
- 52(P-19) フタバガキ科植物のスチルベンオリゴマーの構造(第3報)(ポスター発表の部)
- 76(P-33) フタバガキ科およびグネツム科植物のスチルベンオリゴマーの構造と生物活性(ポスター発表の部)
- 83(P-83) フタバガキ科植物のスチルベンオリゴマーの構造と生物活性(ポスター発表の部)
- P-23 南米産薬用植物Pau ferro由来のフラボノイド類 : その構造と多様な生理活性(ポスター発表の部)
- 79(P-73) Procyanidin Oligomerの分子間及び分子内縮合反応による立体選択的合成と構造-活性相関(ポスター発表の部)
- 80(P-8) Procyanidin Oligomerの立体選択的合成研究(ポスター発表の部)
- Phytochemical Studies on Meliaceous Plants. VII. The Structures of Two New Ionone Glucosides from Melia toosendan SIEB. et ZUCC. and a Novel Type of Selective Biooxidation by a Kind of Protease
- THE STRUCTURES OF TWO NEW IONONE GLUCOSIDES FROM MELIA TOOSENDAN AND A NOVEL TYPE OF SELECTIVE BIO-OXIDATION
- 96(P35) 植物由来のトポイソメラーゼII阻害活性を有するポリフェノール類(ポスター発表の部)
- Evaluation of Blood Pressure Measured by Tail-Cuff Methods (without Heating) in Spontaneously Hypertensive Rats(Pharmacology)
- Effects of Ginkgo Biloba Extract Feeding on Salt-Induced Hypertensive Dahl Rats(Pharmacology)
- Safety of Dietary Supplements:Chronotropic and Inotropic Effects on Isolated Rat Atria
- P2Y Receptor-Mediated Ca^ Signaling Increases Human Vascular Endothelial Cell Permeability
- Characterization of Prejunctional Purinoceptors Inhibiting Noradrenaline Release in Rat Mesenteric Arteries
- Structures of New and Known Cyanoglucosides from a North American Plant, Purshia tridentata DC.
- Abietane Diterpenes from Clerodendron cyrtophyllum
- Phenolic Constituents in Erythrina x bidwilli and Their Activity against Oral Microbial Organisms
- A Chlorine-Containing neo-Clerodane Diterpene from Teucrium pernyi
- Studies no Inhibitors of Skin Tumor Promotion. XI. Inhibitory Effects of Flavonoids from Scutellaria baicalensis on Epstein-Barr Virus Activation and Their Anti-tumor-Promoting Activities
- Two New β-Hydroxychalcones from the Root Bark of Pongamia pinnata
- Comparison of Aristolochia Species with Chemical Constituents
- Chemotaxonomy of the Genus Citrus Based on Polymethoxyflavones
- Further Study on Two Chemical Races of Salix sachalinensis FR. SCHMIDT
- Two New neo-Clerodane Diterpenes in Ajuga decumbens
- 108(P-50) Juniperus属植物のフェノール性成分の構造と生物活性(ポスター発表の部)
- 50(P-19) Welwitschia mirabilisのスチルベノイドの構造(ポスター発表の部)
- 特異なポリフェノール-植物スチルベンオリゴマーの化学と多様な生物活性
- 52(P-15) グネツム科植物のスチルベンオリゴマーの構造と生物活性(ポスター発表の部)
- 69(P47) オトギリソウ科植物成分研究と生理活性(ポスター発表の部)
- Clerodane Diterpenoids from Ajuga decumbens
- P-34 マメ科クララ属植物由来のスチルベンオリゴマーの構造(ポスター発表の部)
- Two Novel Resveratrol Trimers, Leachianols A and B, from Sophora leachiana
- P-33 Sophora属植物由来のフラボノスチルベン及びオリゴスチルベンの構造(ポスター発表の部)
- II-C-4 呉茱萸の生薬薬理学的品質評価研究
- Structure of a New Acylated Flavonoid Glycoside, Euryanoside, from Flowers of Eurya japonica THUNB.
- 3(A-3) 脂肪細胞分化誘導阻害物質ミコフェノール酸及び誘導体の分子標的(口頭発表の部)
- Pentosidine生成阻害物質の探索
- 32 新規神経突起伸長阻害物質インドカルバゾスタチン類の構造と活性(口頭発表の部)
- 32 作物における生体機能調節物質に関する研究
- 富山県産キノコの生産する生理活性物質の探索
- 野菜における生体機能調節物質の探索に関する研究
- マウス網内系の貪食能に及ぼす淫羊〓の影響
- A New Ionone Glucoside and a New Phenylpropanoid Rhamnoside from Stems of Ampelopsis brevipedunculata (MAXIM.) TRAUTV.
- Phytochemical Studies of Seeds of Medicinal Plants. I. : Two Sulfated Triterpenoid Glycosides, Sulfapatrinosides I and II, from Seeds of Patrinia scabiosaefolia FISCHER
- Effect of Quinine Solutions on Intracellular Ca^Levels in Neuro-2a Cells : Conventional Physiological Method for the Evaluation of Bitterness(Miscellaneous)
- ウマノスズクサ亜属とオオバウマノスズクサ亜属(ウマノスズクサ科)24分類群の染色体数に関する研究
- matKシークエンスに基づくウマノスズクサ属(ウマノスズクサ科)の分子系統
- Phytochemical Studies on Meliaceous Plants. VIII. Structures and Inhibitory Effects on Epstein-Barr Virus Activation of Triterpenoids from Leaves of Chisocheton macrophyllus KING
- Chemotaxonomic Studies on the Genus Citrus. I. Distribution of Flavones in the Subgroup Microcarpa(Pharmacognosy,Chemical)
- Two New Hopane-Triterpene Glycosides from a Fern, Diplazium subsinuatum (WALL. ex HOOK. et GREV.) TAGAWA
- Phytochemical Studies of Seeds of Medicinal Plants. III.Ursolic Acid and Oleanolic Acid Glycosides from Seeds of Patrinia scabiosaefolia FISCHER
- Phytochemical Studies of Seeds of Medicinal Plants. II. A New Dihydroflavonol Glycoside and a New 3-Methyl-1-butanol Glycoside from Seeds of Platycodon grandiflorum A. DE CANDOLLE
- TWO NEW POTENT INHIBITORS OF XANTHINE OXIDASE FROM LEAVES OF PERILLA FRUTESCENS BRITTON VAR. ACUTA KUDO
- A Novel Flavonol Glycoside in the Leaves of Epimedium sempervirens
- Phytochemical Studies on Meliaceous Plants. IV. : Structure of a New Pregnane Glycoside, Toosendanoside, from Leaves of Melia toosendan SIEB. et ZUCC.
- 摂南大学薬学部附属薬用植物園の外部への情報発信について (特集 植物園運営における、普及・啓発活動の事例--シンポジウム、講演会、研修会、展示会など)
- Epimedium属フラボノール配糖体の季節的変動
- Flavonol Glycosides in Epimedium Species
- Resin Glycosides. XVI. Marubajalapins I-VII, New Ether-Soluble Resin Glycosides from Pharbitis purpurea
- NOVEL ISOCOUMARIN DERIVATIVES FROM ACHLYS TRIPHYLLA (BERBERIDACEAE)
- Synthesis and Structure Confirmation of the Complex Flavonoids in Pityrogramma calomelanos
- Four New Insect Antifeedant neo-Clerodane Diterpenoids, Ajugacumbins A, B, C and D, from Ajuga decumbens
- Structure-Activity Correlation of Flavonoids for Inhibition of Bovin Lens Aldose Reductase
- 岐阜薬科大学標本目録(12) : 交換〓葉標本目録-中国-(2)
- Sophora属の化学成分
- Chemotaxonomy of the Genus Euchresta. III. Three New Flavonoids in the Roots of Euchresta japonica
- 岐阜薬科大学標本目録(11) : 交換〓葉標本目録-中国-(1)
- 黄苓属フラボノイドの合成(第2報)2', 6'-二置換型フラボンの合成
- TWO NEW ANTINEOPLASTIC DITERPENES FROM TAXUS MAIREI(Communications to the Editor)
- 中国産ハスノハカズラ属植物の化学成分と化学分類学の研究
- Two New Triterpenoid Glycosides from Leaves of Ilex chinensis SIMS(Organic,Chemical)
- Chemical Evaluation of Betula Species in Japan. IV. Constituents of Betula davurica
- Chemical Evaluation of Betula Species in Japan. II. Constituents of Betula platyphylla var. japonica
- Discovery of R-142086 as a Factor Xa (FXa) Inhibitor : Syntheses and Structure-Activity Relationships of Cinnamyl Derivatives
- Cinnamyl Derivatives : Synthesis and Factor Xa (FXa) Inhibitory Activities
- Cinnamylindoline Derivatives : Synthesis and Factor Xa (FXa) Inhibitory Activities
- Indoline Derivatives II : Synthesis and Factor Xa (FXa) Inhibitory Activities
- Indoline Derivatives I : Synthesis and Factor Xa (FXa) Inhibitory Activities
- [2-(ω-Phenylalkyl)phenoxy]alkylamines III : Synthesis and Selective Serotonin-2 Receptor Binding (2)
- [2-(ω-Phenylalkyl)phenoxy]alkylamines II : Synthesis and Selective Serotonin-2-Receptor Binding
- [2-(ω-Phenylalkyl)phenoxy]alkylamines : Synthesis and Dual Dopamine_2 (D_2) and 5-Hydroxytryptamine_2 (5-HT_2) Receptor Antagonistic Activities
- Three New Diarylheptanoid Glycosides from Alnus japonica
- Chemical Evaluation of Betula Species in Japan. VI. Constituents of Betula schmidtii
- Chemical Evaluation of Betula Species in Japan. V. Constituents of Betula ovalifolia
- Three New Hemiterpene Glycosides from Ilex macropoda
- Two New Acyl-Phloroglucinols from Dryopteris atrata
- Chemical Evaluation of Betula Species in Japan. III. Constiutents of Betula maximowicziana
- Distribution of Lignans in Blechnaceous Ferns in New Zealand(Natural Medicine Note)
- 5-O-Glucosylated Kaempferols from the Fern Dryopteris dickinsii
- Two New Phytoecdysteroids from the Fern Schizaea dichotoma
- 日本産オウレン属植物の成分とその変異
- ニクズク(ニクズク科)の生植物の日本への導入について
- Effects of Short-term Ginkgo Biloba Extract Feeding on Hypotensive Action of Nicardipine in Rats
- Insulin Induces Internalization of the Plasma Membrane 5-Hydroxytryptamine_ (5-HT_) Receptor in the Isolated Human Endothelium-Denuded Saphenous Vein via the Phosphatidylinositol 3-Kinase Pathway
- タイトル無し
- P-28 フタバガキ科植物Vatica albiramisのスチルベンオリゴマーの構造(ポスター発表の部)