77(P-34) 海水魚ヤナギベラ由来放線菌の産生する新規細胞毒性物質の化学構造(ポスター発表の部)
スポンサーリンク
概要
- 論文の詳細を見る
Based on the fact that some of the bioactive materials isolated from marine animals have been produced by bacteria, we have focused our attention on new antitumor materials from microorganisms inhabiting the marine environment. As part of our ongoing search for new antitumour metabolites produced by microorganisms from marine organisms, halichoblelide A (1)-C (3) have been isolated from a strain of Streptomyces hygroscopicus OUPS-N92 originally separated from the marine fish Halichoeres bleekeri. Compounds 1-3 were assigned the molecular formulae C_<54>H_<85>O_<19>, C_<51>H_<84>O_<15> and C_<50>H_<82>O_<15>, respectively, as deduced from [M+Na]^+ peaks in HRSIMS. The absolute stereostructures for these metabolites have been elucidated on the basis of spectroscopic analyses using 1D and 2D NMR techniques and CD spectra for the dibenzoates of the degradation products of these compounds. All these compounds exhibited potent cytotoxicity in the P388 lymphocytic leukemia test system in a cell culture.
- 天然有機化合物討論会の論文
- 2001-09-01
著者
関連論文
- P-27 海水魚由来真菌の産生する細胞毒性物質の構造(ポスター発表の部)
- Phytogrowth-Inhibitory Activities of 2-Thiophenecarboxylic Acid and Its Related Compounds
- ANTIFEEDANTS FOR THE LARVAE OF THE YELLOW BUTTERFLY, EUREMA BECABE MANDARINA, IN LYCORIS RADIATA
- 41(P-1) アメフラシ由来真菌の産生する細胞接着阻害物質(ポスター発表の部)
- 10 海洋生物由来の菌類の産生する抗腫瘍性物質(口頭発表の部)
- 93 海水魚由来の真菌の産生する細胞毒性物質および新規キナゾリン誘導体の構造(口頭発表の部)
- Juvabione Analogs from Abies sachalinensis (FR. SCHM.) MAST. II
- 67(P-51) ムラサキウニ由来真菌の産生する新規細胞毒性物質の化学構造(ポスター発表の部)
- 77(P-34) 海水魚ヤナギベラ由来放線菌の産生する新規細胞毒性物質の化学構造(ポスター発表の部)
- 101(P50) 海藻由来Penicillium属真菌の細胞毒性代謝産物の構造(ポスター発表の部)
- 32 海洋動物由来真菌の抗腫瘍性代謝産物(口頭発表の部)
- 12 海洋生物由来のPenicillium属真菌の産生する細胞毒性物質(口頭発表の部)
- 20 海綿由来真菌の新規細胞毒性代謝産物の化学構造とgymnastatin Iの全合成(口頭発表の部)
- Cytotoxic Activity of Marine Algae and a Cytotoxic Principle of the Brown Alga Sargassum tortile
- Plant Constituents Biologically Active to Insects. VI. : Antifeedants for Larvae of the Yellow Butterfly, Eurema hecabe mandarina, in Osmunda japonica. (2)
- New Triterpenes from a Chinese Medicine, Goreishi
- Cytotoxic Triterpenes from a Chinese Medicine, Goreishi
- Plant Constituents Biologically Active to Insects. V. Antifeedants for the Larvae of the Yellow Butterfly, Eurema hecabe mandarina, in Osmunda japonica. (1)
- Magnesium-Induced Shifts in the Proton Magnetic Resonance Spectra of Phenols
- Plant Constituents Biologically Active to Insects. IV. Antifeedants for the Larvae of the Yellow Butterfly, Eurema hecabe mandarina, in Arachniodes standishii
- The Effect of the Alkaline Earth Salts on the NMR Spectrum of Phenols
- ハスノハギリ(Hernandia ovigera L.)の種子成分研究(第2報)リグナン成分ならびに関連物質についての2,3の反応
- C-Glycosylflavones in Lespedeza cuneata
- ハスノハギリ(Hernandia ovigera L.)の種子成分研究
- Plant Constituents biologically Active to Insects. I. Feeding Stimulants for the Larvae of the Yellow Butterfly, Eurema hecabe mandarina. (1)
- 2,3-Methylenedioxynaphthalene の合成
- Plant Constituents biologically Active to Insects. II. Juvabione Analogs from Abies sachalinensis MAST. (1).
- 酸漿根のアルカロイド研究(第2報)
- NarcotinediolおよびHydrastinediolのSnCl_2-HClによる反応成績体
- タウタンパク質に存在する微小管結合ドメインの溶液構造とフィラメント形成機構に関する研究
- P-42 CD Cotton効果とFD-838及びその7つの立体異性体の絶対配置との相関(ポスター発表の部)
- P-32 海水魚由来真菌の産生する新規azaphilone類の絶対構造(ポスター発表の部)