馬杉腎炎に於けるアレルギーの問題に就いて : 第5報病理組織學的變化に就いて

概要

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Three kinds of specimen were made from the following three groups: the first is those of the kidneys from the rabbits which had been sensitized previously with the normal duck serum and under went an intravenous injection of nephrotoxin 12 or 30 hours ago: the second is of the kidney from a young, little rabbit which under, went an intravenous injection of a large amount of nephrotoxin 6 hours ago: the third is that of a rabbit which under went nephrotoxin injection into the one side its renal artery 14 days ago. In each specimen changes of the kidney appeared chiefly in the glomeruli. Namely congestion, or anemia and cell-infiltration in the loops of Henle, enlargement and desquamation of the endotheliar cells of glomerular capsules were observed. These histological changes essentially not different from tho,e of the Masugi-nephritis. On the 14th days after the injection of nephrotoxin into the one side of the renal, artery, both kidneys were compared with each other and observed histologically. The kidney which under went the injection showed remarkable changes intensively, compared with the other side. Acceding to the authors opinion, a large amount of nephrotoxin is attached to the injected side soon after the inoculation and normal anaphlaxis occurs intensively by means of the duck serum contained in the nephrotoxin attached to the kidney.
社団法人日本循環器学会の論文
1949-11-20