Cardiorespiratory Fitness and Serum Lipoprotein and Apolipoprotein Profiles in Men and Women

概要

論文の詳細を見る
Background : Previous studies have suggested that vigorous physical activity is associated with a reduced risk of coronary heart disease (CHD). However, the relationship of cardiorespiratory fitness to apolipoproteins has not been well-investigated. Objective : In order to document possible variations of lipoproteins and apolipoproteins in relation to cardiorespiratory fitness, 234 healthy men and 240 women of cardiorespiratory fitness were examined and the serum concentrations of lipoprotein and apolipoprotein A-1, B, and E investigated. Methods : Cardiorespiratory fitness using VO_2max, estimated by sub-maximal cycle test, blood pressure, lipid, and lipoprotein profiles, apolipoprotein A-1 (Apo A-1), Apolipoprotein B (Apo B), and other major CHD risk factors were determined. The frequency of weekly leisure activity was reported on in a questionnaire. Results : Prominent findings for VO_2max were positive associations with HDL-c and Apo A-1 and negative associations with age, triglycerides (TG), Apo-B and Apo-E in both sexes. Also, we found that the activity group had higher levels of VO_2max, serum high density lipoprotein cholesterol (HDL-c) and Apo-A1 to the sedentary group in both genders. Conclusions : The major finding of this study was that being cardiorespiratory physically fitter improves apolipoprotein profiles, which, in turn, could provide protection against CHD.
愛知学泉大学の論文