Prescribing Patterns during Pregnancy at Tokushima University Hospital
スポンサーリンク
概要
- 論文の詳細を見る
The purpose of this study was to investigate the drugs prescribed for pregnant women at Tokushima University Hospital in Japan, and to evaluate the risks associated with the use of these drugs during pregnancy according to the pregnancy risk classification systems of the PDA, ADEC and that used in manufacturers' package inserts. Of 496 female outpatients who gave birth at Tokushima University Hospital, 81% had been prescribed at least one drug, and the mean was 4.0 drugs per patient. Analysis of the prescriptions revealed a pattern of drug use very different from that in other countries, in that Kampo (Japanese herbal) medicines were also prescribed. For more than half of the oral drugs prescribed, risks were not given in the PDA and/or ADEC pregnancy risk systems. In addition, there was no listing of pregnancy risks in the package inserts of 20 drugs. We therefore consider it to be very important to develop a globally harmonized system for evaluating the risks associated with prescription drugs taken during pregnancy.
- 日本医療薬学会の論文
- 2007-04-10
著者
-
山内 あい子
徳島大学薬学部
-
山内 あい子
Department Of Pharmaceutical Information Science Graduate School Of Pharmaceutical Science The Unive
-
Yamauchi Aiko
Graduate School Of Pharmaceutical Sciences The University Of Tokushima
-
IRAHARA Minoru
Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushim
-
MAEDA Kazuhisa
Department of Obstetrics and Gynecology, The University Tokushima, School of Medicine
-
YAMANO Shuji
Department of Veterinary Anatomy Faculty of Veterinary Medicine Hokkaido University
-
KIHARA Masaru
Graduate School of Pharmaceutical Sciences, The University of Tokushima
-
SAKAMOTO Kumiko
Graduate School of Pharmaceutical Science, The University of Tokushima
-
Irahara Minoru
Department Of Obstetrics And Gynecology Institute Of Health Biosciences The University Of Tokushima
-
Irahara Minoru
Department Of Obstetrics And Gynecology The University Of Tokushima School Of Medicine
-
Yamano Shuji
Department Of Obstetrics And Gynecology The University Of Tokushima School Of Medicine
-
Yamano Shuji
Department Of Obstetrics And Gynecology School Of Medicine University Of Tokushima
-
Kihara Masaru
Fac. Of Pharmaceutical Sciences The Univ. Of Tokushima
-
Maeda Kazuhisa
Department Of Obstetrics And Gynecology The University Of Tokushima School Of Medicine
-
Maeda Kazuhisa
Department Of Neuro-psychiatry And Department Of Clinicla Pharmacology Faculty Of Medicine Tottori U
-
Hibino Yuki
Graduate School of Pharmaceutical Sciences, The University of Tokushima
-
Hibino Yuki
Graduate School Of Pharmaceutical Sciences The University Of Tokushima
-
Sakamoto Kumiko
Fac. Of Pharmaceutical Sciences The Univ. Of Tokushima
-
Maeda Kazuhisa
Department Of Internal Medicine And Rehabilitation Science Tohoku University Graduate School Of Medi
-
YAMAUCHI Aiko
Graduate School of Pharmaceutical Science, The University of Tokushima
関連論文
- Accumulation of common polymorphisms is associated with development of hypertension : a 12-year follow-up from the Ohasama study
- Impaired Insulin Secretion in Four Tangier Disease Patients with ABCA1 Mutations
- Uncontrolled hypertension based on morning and evening home blood pressure measurements from the J-HOME study
- The association between masked hypertension and waist circumference as an obesity-related anthropometric index for metabolic syndrome : the Ohasama study
- PE-152 Adiponectin Deficiency Suppresses ABCA1 Expression and ApoA-I Synthesis in the Liver(Atherosclerosis, basic(04)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- 29-P3-34 徳島大学薬学部OSCEトライアル実施体制の確立と検証(薬学教育,社会の期待に応える医療薬学を)
- P-523 急速静脈内投与後のセフェム系抗生物質のCSF移行性評価(9.薬物動態(基礎と臨床),"薬剤師がつくる薬物治療"-薬・薬・学の連携-)
- 徳島大学病院におけるTPN処方設計支援ソフトの使用評価と改良
- Evaluation of a Homogeneous Assay for Measuring LDL-cholesterol in Hyperlipidemic Serum Specimens
- PE-151 Adiponectin Promotes Cholesterol Efflux from Human Macrophages throuth ABCA1-dependent Pathway(Atherosclerosis, basic(04)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Proposal of a Risk-Stratification System for the Japanese Population Based on Blood Pressure Levels : The Ohasama Study
- P-712 静脈経腸栄養計算支援ソフトの作成およびその活用(14.輸液、経腸栄養管理1,医療薬学の未来へ翔(はばた)く-薬剤師の薬剤業務・教育・研究への能動的関わり-)
- Comparison of Arterial Functional Evaluations as a Predictor of Cardiovascular Events in Hypertensive Patients : The Non-Invasive Atherosclerotic Evaluation in Hypertension (NOAH) Study
- Electrocardiographic abnormalities and home blood pressure in treated elderly hypertensive patients : Japan home versus office blood pressure measurement evaluation in the elderly (J-HOME-Elderly) study
- High blood pressure worsens age-related increases in arterial stiffness evaluated by pulse wave velocity in subjects with lifestyle-related diseases
- β3-Adrenergic Receptor Trp64arg Polymorphism Is Related with Endothelial Dysfunction via Increased Oxidized Stress in Proportion to Increasing Sympathetic Nervous Activity
- Intercellular Adhesion Molecule-1 G241R Polymorphism Influences Increasing Arterial Stiffness
- Single Nucleotide Polymorphisms of Ligand-Receptor System of Monocyte Chemoattractant Protein-1 Influence Different Arterial Dysfunctions with Serum Interleukin-15 Elevation
- Plasma levels of inflammatory related substances are correlated with severity of aortic stiffness and endothelial dysfunction in hypertensive patients
- Plasma level of 8-hydroxydeoxyguanosine, a marker of oxidative stress, was correlated to endothelial dysfunction in hypertensive patients
- Serum hepatocyte growth factor concentration is a specific marker of endothelial dysfunction in humans
- 29-P3-21 注射用セフェム系抗生物質のラット脳脊髄腔液移行性評価(薬物治療,社会の期待に応える医療薬学を)
- Clinical Significance of High-Molecular Weight Form of Adiponectin in Male Patients With Coronary Artery Disease
- Pharmacological assessment of ARTCEREB_【○!R】 irrigation and perfusion solution for cerebrospinal surgery using primary cultures of rat brain cells
- Evaluation of Morning Blood Pressure Elevation and Autonomic Nervous Activity in Hypertensive Patients Using Wavelet Transform of Heart Rate Variability
- ACE2 Mutant Mice Increase Cardiac Angiotensin II and Increase Incidence of Heart Failure in Response to Pressure Overload (Heart Failure, Basic 7 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- B31 医薬品安全性情報コミュニティ・データベースシステム : 妊娠と薬に関する安全性情報の共有に向けて(セッションB3(医学・医薬情報),一般発表概要:各セッション報告,INFOPRO2006)
- 「妊娠と薬」に関する意識調査 : 薬剤師,薬学生,研究者の場合
- 01P2-049 医薬品安全性情報コミュニティにおける薬物催奇形性情報データベースの試験公開(医薬品情報・データベース,医療薬学の扉は開かれた)
- 01P2-048 医薬品安全性情報コミュニティの紹介(医薬品情報・データベース,医療薬学の扉は開かれた)
- 双方向・成長型薬物催奇形性情報コミュニティの構築
- PJ-679 Clinical Significance of High Molecular Weight Form of Adiponectin in Male Patients with Coronary Artery Disease(Diabetes / Obesity / Metabolic syndrome(14)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation
- Practice and awareness of physicians regarding home blood pressure measurement in Japan
- Masked Hypertension Determined by Self-Measured Blood Pressure at Home and Chronic Kidney Disease in the Japanese General Population : The Ohasama Study
- Fruit and Vegetable Consumption and the Risk of Hypertension Determined by Self Measurement of Blood Pressure at Home : The Ohasama Study
- Difference between Home and Office Blood Pressures among Treated Hypertensive Patients from the Japan Home versus Office Blood Pressure Measurement Evaluation (J-HOME) Study
- 29-P2-78 地域保険薬局における定期来局患者および処方箋調剤に関する実態調査とファーマシューティカル・ケアの実践(医薬品管理,社会の期待に応える医療薬学を)
- P-25 ハロゲン化炭化水素の腎細胞毒性に対する N-acetylcysteine の保護作用
- Reproducibility of luteinizing hormone hypersecretion in different phases of the menstrual cycle in polycystic ovary syndrome
- Transition of Leptin Receptor Expression during Pubertal Development in Female Rat Pituitary
- Diagnostic Performance of Serum Total Testosterone for Japanese Patients with Polycystic Ovary Syndrome
- Comparison and Problems of Measured Values of LH, FSH, and PRL among Measurement Systems
- P1-571 徳島大学における薬学部・薬剤部連携による病院実務実習の実践(一般演題 ポスター発表,薬学教育(実務実習),臨床から学び臨床へと還元する医療薬学)
- OE-208 Chylomicron Remnants are Increased in CD36 Deficiency at Postprandial State(Lipid disorders(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- 01P2-052 医薬品商品名の由来データベースの作成と医療薬学教育への応用(医薬品情報・データベース,医療薬学の扉は開かれた)
- 30-P2-190 薬物のヒト胎盤通過性に関する構造活性相関解析と妊婦に処方された医薬品の胎児移行性評価(医薬品情報,社会の期待に応える医療薬学を)
- P-694 徳島大学病院における妊婦に対する処方医薬品とその胎児危険度評価(13.薬品管理、使用状况調査2,医療薬学の未来へ翔(はばた)く-薬剤師の薬剤業務・教育・研究への能動的関わり-)
- 27-04-07 抗癌剤耐性ヒト非小細胞肺癌細胞における cisplatin によるアポトーシス誘導機構
- O-49 ヒト非小細胞肺癌細胞の抗癌剤感受性と多剤排出トランスポーターの発現
- O-108 多剤併用の肝・腎機能に及ぼす影響 : 臨床検査値からの評価
- Triple Marker Screening for Trisomy 21, Trisomy 18 and Open Neural Tube Defects in Singleton Pregnancies of Native Japanese Pregnant Women
- Dimeric Inhibin A as a Fourth Marker for Down's Syndrome Maternal Serum Screening in Native Japanese Women
- DISTRIBUTION OF LYMPHATIC TISSUES IN DUCK CAECA
- Relationship of dysregulation of glucose metabolism with white-coat hypertension : the Ohasama study
- Practice and awareness of physicians regarding casual-clinic blood pressure measurement in Japan
- Carbonated soft drinks and carbonyl stress burden
- Perfusion fluids used in neurosurgery affect cerebrospinal fluid and surrounding brain parenchyma in the rat ventriculocisternal perfusion model
- Rapid Detection of Chromosome Aneuploidies by Prenatal Interphase FISH (Fluorescence in situ Hybridization) and Its Clinical Utility in Japan
- 4 年次卒前長期病院実習の現時点での評価
- A SIMPLE AND RAPID ASSAY OF SERUM LUTEINIZING HORMONE BY HEMAGGLUTINATION REACTION
- A Plasma Protein Abundantly Expressed in Visceral Fat, Visfatin Modulates Inflammatory Response in Human Monocyte-derived Macrophages
- 医薬品安全性情報コミュニティの構築にむけて
- Soybean Oil Fat Emulsion to Prevent TPN-Induced Liver Damage : Possible Molecular Mechanisms and Clinical Implications
- Major Role of Soybean Oil in Preventing Decrease in CYP4A1 mRNA Content Relative to PPARα mRNA Down-Regulation in Infant Rats(Pharmacology)
- Soybean Oil in Total Parenteral Nutrition Maintains Albumin and Antioxidant Enzyme mRNA Levels(Biopharmacy)
- Expression of Multidrug Resistance Proteins and Accumulation of Cisplatin in Human Non-small Cell Lung Cancer Cells(Biopharmacy)
- Role of Soybean Oil Fat Emulsion in the Prevention of Hepatic Xenobiotic Transporter mRNA Up- and Down-Regulation Induced by Overdose of Fat-free Total Parenteral Nutrition in Infant Rats
- Soybean Oil Fat Emulsion Prevents Cytochrome P450 mRNA Down-Regulation Induced by Fat-Free Overdose Total Parenteral Nutrition in Infant Rats(Biopharmacy)
- ニューラルネットワークを用いたドナウ川の水質解析−OECDレポートを用いて−
- 線形多変量解析を用いた徳島吉野川の水質の解析
- Construction of a Model for Water Purification Mechanisms in a River by Using a Neural Network Approach
- 医薬品安全性情報コミュニティ・データベースシステム： : 妊娠と薬に関する安全性情報の共有に向けて
- Extraction of a Parameter as an Index to Assess Water Quality of the Tamagawa, Tokyo, Japan, by Using Neural Networks and Multivariate Analysis
- A Structural Similarity Evaluation by SimScore in a Teratogenicity Information Sharing System
- 妊娠期の薬物療法--その実態と母児への影響 (特集 "女性とくすり"の留意点)
- Recombinant follicle-stimulating hormone (follitropin alfa) versus purified urinary follicle-stimulating hormone in a low-dose step-up regimen to induce ovulation in Japanese women with anti-estrogen-ineffective oligo- or anovulatory infertility : results
- Recombinant follicle-stimulating hormone (follitropin alfa) for ovulation induction in Japanese patients with anti-estrogen-ineffective oligo- or anovulatory infertility : results of a phase II dose-response study
- New Entry of Coupling Reaction of Phenacylamine Derivatives with Silylstannane
- Synthesis and Biological Evaluation of 7-Hydroxy-3,4-diphenyl-1,2-dihydroisoquinolines as New 4-Hydroxytamoxifen Analogues
- Prescribing Patterns during Pregnancy at Tokushima University Hospital
- Hormonal and histological study on irregular genital bleeding in patients with endometriosis during treatment with dienogest, a novel progestational therapeutic agent
- Laparoscopic proximal tubal division can preserve ovarian reserve for infertility patients with hydrosalpinges
- Impact of laparoscopic cystectomy of fecundity of infertility patients with ovarian endometrioma
- Effect of Advanced Pharmaceutical Services for Chemotherapy on Length of Hospital Stay
- THE LYMPHATIC SYSTEM OF THE CORPUS PARACLOACALIS VASCULARIS AND THE SECOND FOLD IN THE MALE DOMESTIC FOWL
- FINE STRUCTURES OF CORPUS PARACLOACALIS VASCULARIS IN COCKS
- ANATOMICAL STUDIES OF CORPUS PARACLOACALIS VASCULARIS IN COCKS
- Influence of Water-Immersion Stress on Catecholaminergic Systems in Rat Brain
- Effects of Transforming Growth Factor-β on the Production of Parathyroid Hormone-Related Peptide in a Human Ovarian Cancer Cell Line in vitro
- A MORPHOLOGICAL STUDY ON THE CORPUS PARACLOACALIS VASCULARIS IN THE DOMESTIC FOWL
- The role of blood in early endometrial-peritoneal interactions in a syngeneic mouse model of endometriosis
- Project of the Database Construction for Teratogenic Agents : Construction of the Growing Information-Community for Teratogenic Agents(WORKSHOP 2 : QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS AND PREDICTION OF TOXICITY)
- P-1218 薬学部教員が病院実習「情報を正しく使う」を実施して(一般演題 ポスター発表,薬学教育(実務実習),Enjoy Pharmacists' Lifestyles)
- A case of placental polyp treated with an intraoperative injection of prostaglandin F_ followed by hysteroscopic resection
- Fasting reduces the kiss1 mRNA levels in the caudal hypothalamus of gonadally intact adult female rats
- The impact of systematic para-aortic and pelvic lymphadenectomy on survival in patients with optimally debulked ovarian cancer
- ISP-7-4 The effect of neonatal nutritional condition on the timing of puberty in normal and IUGR female rats(Group 7 Reproduction,IS Poster,International Session)
- P2-396 NSAIDs服用による発癌抑制とCOX遺伝子多型の影響に関するメタアナリシス(薬物治療と遺伝子多型,ポスター,一般演題,岐路に立つ医療〜千年紀の目覚め〜よみがえれ!ニッポン!薬の改革は我らが手で!)
- P1-435 妊婦・授乳婦の漢方薬治療に関する安全性情報データベースの構築(医薬品情報・データベース,ポスター,一般演題,岐路に立つ医療〜千年紀の目覚め〜よみがえれ!ニッポン!薬の改革は我らが手で!)
- Delay in the onset of puberty of intrauterine growth retarded female rats cannot be rescued with hypernutrition after birth