The Population of CD40L-expressing Cells was Slightly but not Significant Decreased in Lymphoid Tissues of Collagen Induced Arthritic Mice Treated with Hochu-Ekki-To

スポンサーリンク

概要

• 論文の詳細を見る

• Objective : To clarify the mechanism of the action of Hochu-Ekki-To (HET) on collagen-induced arthritic (CIA) mice by analyzing the CD40L-expressing cells population. Methods : CIA was induced in male DBA/1J mice by immunization with two injections of bovine type II collagen (CII). HET or water was orally administered. The subpopulations of lymphocytes obtained from lymph nodes and spleen were detected at 3 weeks after boost using flow cytometry. Results : Although the population of CD4+CD40L+ cells tended to be decreased in the HET group compared to that in control mice, there was no significant difference between the two groups. These findings were observed in lymphocytes obtained from both lymph nodes and spleen. Conclusion : HET suppresses the development of CIA. These effects may be partially induced via the decrease in the population of CD4+CD40L+ cells, but the role of this action is probably limited.

• 社団法人日本薬学会の論文
• 2007-03-01

著者

• Terasawa Katsutoshi

  群馬大学 医学部医学科統合和漢診療学講座

• Terasawa K

  Dept. Of Japanese Oriental Medicine Graduate School Of Medicine Chiba University

• NIIZAWA Atsushi

  Department of Japanese-Oriental Medicine, Kanebo Memorial Hospital

• Shimada Y

  Dept. Of Japanese Oriental Medicine Faculty Of Medicine University Of Toyama

• KOGURE Toshiaki

  Dept. of Integrated Japanese Oriental Medicine, School of Medicine, Gunma University

• TATSUMI Takeshi

  Dept. of Integrated Japanese Oriental Medicine, School of Medicine, Gunma University

• NIIZAWA Atsushi

  Dept. of Japanese Oriental Medicine, Kanebo Memorial Hospital

• FUJINAGA Hiroshi

  Dept. of Japanese Oriental Medicine, Toyama Prefectural Hospital

• SHIMADA Yutaka

  Dept. of Japanese Oriental Medicine, Faculty of Medicine, University of Toyama

• TERASAWA Katsutoshi

  Dept. of Japanese Oriental Medicine, Graduate School of Medicine, Chiba University

• 嶋田 豊

  Dept. Of Japanese Oriental Medicine Faculty Of Medicine University Of Toyama

• Shimada Y

  Tokyo Inst. Technol. Yokohama Jpn

• Kita T

  Department Of Integrated Japanese Oriental Medicine School Of Medicine Gunma University

• Shimada Y

  Institute Of Multidisciplinary Research For Advanced Materials Tohoku University

• Shimada Yuji

  Microsystem Research Center Precision And Intelligence Laboratory Tokyo Institute Of Technology

• Terasawa Katsutoshi

  Dept. Of Japanese Oriental Medicine Graduate School Of Medicine Chiba University

• Shimada Y

  Tohoku Univ. Sendai Jpn

• 島田 洋蔵

  産業技術総合研究所

• NIIZAWA Atsushi

  富山医科薬科大学医学部和漢診療学教室

• Tatsumi Takeshi

  Dept. Of Integrated Japanese Oriental Medicine School Of Medicine Gunma University

• Niizawa Atsushi

  Dept. Of Japanese Oriental Medicine Kanebo Memorial Hospital

• 嶋田 豊

  富山医科薬科大学医学部和漢診療学

• Terasawa Katsutoshi

  21st Century Coe Program University Of Toyama:department Of Japanese Oriental Medicine Graduate Scho

• Kita T

  Toyama Medical And Pharmaceutical Univ. Toyama Jpn

• Shibagaki Yukari

  富山大学和漢医薬学総合研究所

• 島田 洋蔵

  Dept. Of Japanese Oriental Medicine Faculty Of Medicine University Of Toyama

• Fujinaga Hiroshi

  Dept. Of Japanese Oriental Medicine Toyama Prefectural Hospital

• Shimada Yutaka

  21^<st> Century Coe Program Toyama Medical And Pharmaceutical University

• Terasawa Katsutoshi

  Dept. Of Integrated Japanese Oriental Medicine School Of Medicine Gunma University

• 小暮 敏明

  Dept. of Integrated Japanese Oriental Medicine, School of Medicine, Gunma University

• 巽 武司

  Dept. of Integrated Japanese Oriental Medicine, School of Medicine, Gunma University

• 新沢 敦

  Dept. of Japanese Oriental Medicine, Kanebo Memorial Hospital

• 藤永 洋

  Dept. of Japanese Oriental Medicine, Toyama Prefectural Hospital

• 寺澤 捷年

  Dept. of Japanese Oriental Medicine, Graduate School of Medicine, Chiba University

関連論文

• 157 脳脊髄液減少症に五苓散が有効であった症例(漢方処方・湯液7,一般演題,伝統医学のあるべきかたちとは-世界の潮流と日本の役割-,第59回日本東洋医学会学術総会)
• 切迫流早産に補中益気湯が有効であった1例
• 和漢薬治療が奏効した Wells' 症候群の一症例
• 煎じ薬の調剤の現状と問題点 : 保険調剤薬局に対するアンケート調査による検討
• 五苓散が奏効した帯状疱疹後神経痛の一例
• 疼痛管理が困難であった発作性・反復性下腹部痛に対し柴胡桂枝湯が奏功した2症例
• 清熱補気湯と白虎加桂枝湯の併用が奏効した結節性紅斑の一症例
• 奔豚と思われた諸症状に呉茱萸湯エキスと苓桂朮甘湯エキスの併用が奏効した6症例
• 帰耆建中湯加味を関節リウマチに応用する試み
• 静脈認証システムエラーに当帰四逆加呉茱萸生姜湯が有効であった一例
• 長年持続していた下痢に対して甘草瀉心湯が奏功した2症例
• 滋陰至宝湯治験
• 桂枝加苓朮附湯の関節外症状への応用
• 開腹術後愁訴に対し香蘇散料が有効であった2症例
• 気うつを伴った凍瘡に対する茯苓飲合半夏厚朴湯および半夏厚朴湯の応用
• 桂枝茯苓丸加〓苡仁治験
• 夏バテに対する漢方方剤の使用目標に関する一考察
• 肘後方奔豚湯加味方が突発性難聴に伴うめまいに著効した1例
• 27-326 漢方外来における心身医学的難治症例の治療検討(相補・代替医療1,一般演題(ポスター発表),近未来医療を担う心身医学,第1回日本心身医学5学会合同集会)
• Psychosocial stress enhances IgE-mediated triphasic cutaneous reaction in mice : Antagonism by youkkan-san (a Kampo medicine) and diazepam.
• A Kampo formulation : Byakko-ka ninjin-to (Bai-Hu-Jia-Ren-Sheng-Tang) inhibits IgE-mediated triphasic skin reaction in mice : The role of its constituents in expression of the efficacy.
• Immunopharmacological properties of Oren-gedoku-to (a Kampo medicine, Huang-Lian-Jie-Du-Tang) on contact hypersensitivity reaction in mice
• Psychosocial stress enhances IgE-mediated triphasic cutaneous reaction in mice : Antagonism by Yokukan-san (a Kampo medicine) and diazepam
• Effect of Some Kampo Medicines, Including Tokaku-joki-to(Tao-He-Cheng-Qi-Tang), on IgE-mediated Triphasic Skin Reaction in Passively Sensitized Mice.
• Different Effect of Antiallergic Drugs on IgE-mediated Cutaneous Reaction in Passively Sensitized Mice.
• A Kampo Formulation : Byakko-ka-ninjin-to(Bai-Hu-Jia-Ren-Sheng-Tang)Inhibits IgE-Mediated Triphasic Skin Reaction in Mice : The Role of Its Constituents in Expression of the Efficacy
• Effects of Shimotsu-to(a Kampo medicine, Si-Wu-Tang)and its constituents on triphasic skin reaction in passively sensitized mice.
• A Third-phase Cutaneous(Very Late Phase)Response after Elicitation with Dinitrofluorobenzene in Passively or Actively Sensitized Mice.
• Inhibitory Effects of Triterpenes Isolated from Chuling (Polyporus umbellatus FRIES) on Free Radical-Induced Lysis of Red Blood Cells(Pharmacology)
• Correlation between "oketsu" syndrome and autonomic nervous activity : a diachronic study on the same subjects
• Effect of Keishi-bukuryo-gan on asymptomatic cerebral infarction for short term
• Association of remnant-like lipoprotein particles cholesterol with "oketsu" syndrome
• Effects of Keishibukuryogan on Vascular Function in Adjuvant-Induced Arthritis Rats(Analytical Biochemistry)
• The Population of CD40L-expressing Cells was Slightly but not Significant Decreased in Lymphoid Tissues of Collagen Induced Arthritic Mice Treated with Hochu-Ekki-To
• Cinnamaldehyde Induces Endothelium-Dependent and -Independent Vasorelaxant Action on Isolated Rat Aorta(Pharmacology)
• Chotosan and cerebrovascular disorders : Clinical and experimental studies
• Expression Patterns of Plasma Proteins in Spontaneously Diabetic Rats after Oral Administration of a Kampo Medicine, Hachimi-jio-gan, Using SELDI ProteinChip Platform(Pharmacognosy)
• Inhibitory Effects of Stephania tetrandra S. MOORE on Free Radical-Induced Lysis of Rat Red Blood Cells(Pharmacognosy)
• 香蘇散による耳鳴治療の経験(39耳鼻科・眼科, 第56回日本東洋医学会学術総会)
• Clinical Assessment of Usefulness, Effectiveness and Safety of Keishi-bukuryo-gan on Various Neuropathies : A Case Series
• Effect of Red Ginseng on CO_2 Reactivity in Middle Cerebral Artery in Healthy Human Subjects
• Oren-gedoku-to and Keishi-bukuryo-gan-ryo Inhibit the Progression of Atherosclerosis in Diet-Induced Hypercholesterolemic Rabbits(Pharmacognosy)
• Assessment of effects of traditional herbal medicines on elderly patients with weakness using a self-controlled trial
• DIFFERENCES IN ENDOSCOPIC VIEWS DURING BIOPSY THROUGH THE RIGHT AND LEFT LOWER BIOPSY CHANNELS OF THE UPPER GASTROINTESTINAL ENDOSCOPE
• 051 Effect of Hyolboochuko-tang(血府逐〓湯) on the Prognosis of Patients with Middle Cerebral Artery Stenosis
• Can Kampo Medicines Eradicate Helicobacter Pylori in Clinical Situation ?
• Effects of Curcuma Drugs on Vasomotion in Isolated Rat Aorta(Pharmacognosy)
• Possible Relationship between Livid Telangiectasis on the Colon Mucosa and Abdominal Kampo Diagnosis
• Four cases of panic disorder successfully treated with Kampo (Japanese herbal) medicines : Kami-shoyo-san and Hange-koboku-to
• 1 脳血管障害と漢方(I. 特別講演)(第 10 回日本東洋医学会関東北信越支部新潟県部会)
• Radiation Sensitive Cells Dedifferentiated from a Cultured Human Esophageal Cancer Cell Line
• Amelioration of kidney damage in spontaneously diabetic WBN/Kob rats after treatment with Keishi-bukuryo-gan
• Evaluation of Keishi-bukuryo-gan in a diabetic nephropathy model by comparison with aminoguanidine, butylated hydroxytoluene and captopril
• A study of Kampo medicines in a diabetic nephropathy model
• DP-135-2 Reduction of ESCC progression by vector-based RNA interference against gankyrin oncogene
• 総合医に必要な漢方の基本概念 (総合医に必要な漢方の知識--common diseaseに対する漢方治療) -- (総合医に必要な漢方の基本知識)
• P-250 小児縦隔リンパ管腫に漢方治療が奏効した1例(ポスター 嚢胞性疾患,Science and Art for Sick Children,第46回日本小児外科学会学術集会)
• Time-Dependent Leakage Current Behavior of Integrated Ba_Sr_TiO_3 Thin Film Capacitors during Stressing
• Temperature-Dependent Current-Voltage Characteristics of Fully Processed Ba_Sr_TiO_3 Capacitors Integrated in a Silicon Device
• Si LSI Process Technology for Integrating Ferroelectric Capacitors ( FERROELECTRIC MATERIALS AND THEIR APPLICATIONS)
• Application of Ferroelectric Thin Films to Si Devices (Special Issue on Quarter Micron Si Device and Process Technologies)
• Chotosan Enhances Macrophage Colony-Stimulating Factor mRNA Expression in the Ischemic Rat Brain and C6Bu-1 Glioma Cells(Biochemistry)
• Chotosan, a Kampo Formula, Ameliorates Chronic Cerebral Hypoperfusion-Induced Deficits in Object Recognition Behaviors and Central Cholinergic Systems in Mice
• A report of three cases of diabetic nephropathy satisfactorily treated with traditional herbal medicine
• A third-phase cutaneous (very late phase) response after elicitation with dinitrofluorobenzene in passively or actively sensitized mice
• Thermal Aging Effect in Poled Ferroelectric SrBi_2(Ta,Nb)_2O_9 Capacitors
• Voltage Shift Effect on Retention Failure in Ferroelectric Memories
• Ferroelectric Memory Circuit Technology and the Application to Contactless IC Card(Special Issue on Advanced Memory Devices Using High-ε and Ferroelectric Films)
• Retention Characteristics of a Ferroelectric Memory Based on SrBi_2(Ta, Nb)_2O_9
• Ferroelectric Nonvolatile Memory Technology and Its Applications
• Effect of d-Pseudoephedrine on Cough Reflex and Its Mode of Action in Guinea Pigs
• A case of rheumatoid arthritis complicated by bucillamine-induced nephropathy satisfactorily treated with Kampo medicines
• 29pYH-3 半導体超格子中のブロッホ振動と inversionless gain
• SC-11-3 テラヘルツ分光を用いた半導体中のキャリアダイナミクスと超高周波伝導率の計測
• THz EOサンプリング法を用いた半導体の超高速キャリア速度評価
• 半導体超格子のブロッホ振動 : 非古典的振動子のテラヘルツ利得
• CT-2-5 量子ナノ構造の物理とテラヘルツデバイスへの展開(CT-2.ナノ・メカ・バイオ機能材料のデバイス・システムへの応用の新展開,チュートリアル講演,ソサイエティ企画)
• 量子効果デバイスとテラヘルツゲイン(テラヘルツ帯応用を開拓する材料・デバイス・システム技術)
• 半導体超格子のブロッホゲイン
• Efficacy of Nyoshinsan/TJ-67, a traditional herbal medicine, for menopausal symptoms following surgery and adjuvant chemotherapy for premenopausal breast cancer
• Beneficial effect of complementary alternative medicine on lymphedema with rheumatoid arthritis
• A case of rheumatoid arthritis with a decrease in the serum concentration of soluble CD23 by traditional herbal medicine
• Effects of Eppikahangeto, a Kampo Formula, and Ephedrae herba Against Citric Acid-Induced Laryngeal Cough in Guinea Pigs
• Induction of Inducible Nitric Oxide (NO) Synthase mRNA and NO Production in Macrophages Infected with Influenza A/PR/8 Virus and Stimulated with Its Ether-Split Product
• A case-control study of purple urine bag syndrome in geriatric wards
• Additional Inhibitory Effect of Tea of Tea Extract on the Growth of Influenza A and B Viruses in MDCK Cells
• A case of pustulotic arthro-osteitis successfully treated with Kampo medicines
• Electrogastrographic power ratio in humans is not related to changes in antrum-skin distance but to antral motility
• Effect of Kampo treatment on chronic viral hepatitis on the basis of traditional diagnosis
• 千葉大学における漢方教育 (特集 大学での漢方教育)
• 診断方法および随証治療 (特集 漢方診療のイロハ) -- (ファーストステップ)
• Protective effect of the hooks and stems of Uncaria sinensis against nitric oxide donor-induced neuronal death in cultured cerebellar granule cells
• The examination of endoscopic findings in 221 cases of rheumatoid arthritis treated with Japanese Oriental (Kampo) medicine
• Effects of Keishi-bukuryo-gan (Gui-Zhi-Fu-Ling-Wan) on endothelial function in spontaneously hypertensive rats
• Evaluation of Numerical Aperture and Focusing Characteristics of Planar Microlens for Optical Interconnects : Optics and Quantum Electronics
• Parallel Optical-Transmission Module Using Vertical-Cavity Surface-Emitting Laser Array and Micro-Optical Bench (MOB) : Optics and Quantum Electronics
• Collimation Characteristics of Planar Microlens for Parallel Optical Interconnect
• Additive Effects of AlN and MgO on FePt Nanoparticle Assembly
• Magnetic Anisotropy Energy of L1_0 CoPt-B Thin Films Elongated c-axis
• Inhibitory effects of Cinnamomi Cortex and cinnamaldehyde on oxygen-derived free radical-induced vasocontraction in isolated aorta of spontaneously hypertensive rats

もっと見る 閉じる

スポンサーリンク