実験的に惹起した慢性辺縁性歯肉炎における歯肉上皮の細胞代謝に関する研究

概要

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The effect of chronic inflammation on the turnover of the gingival epithelium of the mouse was autoradiographically studied, using the H^3-thymidine. Inflammation was artifically induced by applying croton oil to the site. No differrnce was observed in the migration pattern of the gingival epithelial cell, the cell migration being passive and being almost identical to that in normal. In epithelial attachement, the cell migration was observed from the stratum germinativum toward enamel, margin and/or stratum corneum through the complicated horizontal, vertical and diagonal direction. In downgrowing oral epithelium, migration can be ditected in two ways migration was noted toward the stratum corneum and migration toward the gingival margin gradually approaching the stratum corneum. In oral epithelium, migration was almost in a straight line toward the stratum corneum, while in interdental papilla migration was seemed to be almost identical to that in epithelial attachment. The radioactive index in the experimental group showed higher value at various site of the gingiva than that in the control group, the differnce being statistically significant especially in 12 hours and 3 days. The maximum value in the control group was observed in 24 hours in oral epithelium and downgrowing oral epithelium in 2 days in epithelial attachment and in 24 hours in interdental papilla, but in the experimental group was observed in 12 hours, 24 hours and 24 hours respectively. In the experimental group, the turnover time of the gingival epithelium were 3.7 days in epithelial attachment, 3.4 days in downgrowing oral epithelium, 3.3 days in oral epithelium and 4.2 days in interdental papilla, while in the control group they were 5.4 days, 4.6 days, 5.7 days and 4.7 days, respectively showing a considerable, shortning of time at all site.
特定非営利活動法人日本歯周病学会の論文
1970-09-30

著者

柴田昌治
大阪大学歯学部

実験的に惹起した慢性辺縁性歯肉炎における歯肉上皮の細胞代謝に関する研究

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